Beijing Hanmi Pharmaceutical Co., Ltd.

Mi Young Cha

Maengsup Kim

Jiawang Liu

Gong Li

Nanmeng Song

Yaping Yang

Tao Zhao

Hai Xue

Guoqiang Chen

Jinming Liu

Zhanmei Li

Hongjuan Qiu

Runa Zheng

Jiangcheng Xu

Qinguan Cai

Baoyu Xue

Qingyuan Cai

The present invention relates to a compound inhibiting the activity of an IRAK4 kinase, a pharmaceutical composition thereof, a use thereof in preparing drugs, a method in which same is used for inhibiting the activity of the IRAK4 kinase and a method in which same is used for treating and/or preventing IRAK4 kinase mediated diseases or conditions in mammals (particularly humans). The compound has a structural formula I. 

IRAK4 inhibitor and use thereof

Disclosed are a compound related to inhibiting the activity of an IRAK4 kinase, a pharmaceutical composition thereof, a use thereof in preparing drugs, a method in which same is used for inhibiting the activity of the IRAK4 kinase and a method in which same is used for treating and/or preventing IRAK4 kinase mediated diseases or conditions in mammals (especially humans). The compound has a structural formula I. 

Disclosed are a compound, a stereisomer and a tautomer thereof, a pharmaceutically acceptable salt thereof, and a solvate or a prodrug thereof, which can be used for preventing or treating a ROR&#x3b3; mediated disease. The compound has the structural formula (I). 

N-benzoate group substituted benzopyrroline-2-one derivative and use thereof

The present invention relates to a compound inhibiting the activities of Bruton's tyrosine kinase (BTK) and/or Janus kinase 3 (JAK3), a pharmaceutical composition of the compound, pharmaceutical applications of same, a method for using the compound in inhibiting the activities of BTK and/or JAK3, and a method for using the compound in treatment and/or prevention of BTK- and/or JAK3-mediated diseases or disorders in mammals (especially human). The compound is as represented by structural formula (I). 

Compound inhibiting activities of BTK and/or JAK3 kinases

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Beijing, China

Mi Young Cha