Daewoong Pharmaceutical Co., Ltd.

Mi Ryeong Han

Joon Seok Park

Ji Duck Kim

Kyung A Yu

Yun Soo Yoon

Jun Hee Lee

Sang Shin Lee

Min Hee Cho

Sang Ho Lee

Deok Ki Eom

Yeon Im Lee

Sun Young Kim

In Woo Kim

Yeon Jung Song

Seung Chul Lee

Sun Ah Jun

Chun Ho Lee

Chang Min Park

Youn Jung Yoon

Nam Youn Kim

Ho Bin Lee

Ji Sung Yoon

Eun Ji Koh

Ha Nee Seo

Jakyung Yoo

Yun Soo Na

Min Jae Cho

Kang-Pil Kim

Yeon Jung Park

Yun Ju Oh

The present invention relates to a pyrazolopyrimidine derivative, or a pharmaceutically acceptable salt thereof. The compound according to the present invention can be usefully used for the prevention or treatment of diseases which are associated with kinase inhibitory actions.

Pyrazolopyrimidine derivatives as kinase inhibitor

The present invention provides a 4-methoxy pyrrole derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition containing the same. The 4-methoxy pyrrole derivatives or pharmaceutically acceptable salts thereof according to the present invention have not only excellent proton pump inhibitory activity, gastric damage-inhibiting activity and defensive factor-enhancing effects, but also excellent eradication activity against. Therefore, the 4-methoxy pyrrole derivatives or pharmaceutically acceptable salts thereof can be effectively used for the prevention and treatment of gastrointestinal damage due to gastrointestinal tract ulcer, gastritis, reflux esophagitis or. Moreover, the 4-methoxy pyrrole derivatives or pharmaceutically acceptable salts thereof, have inhibitory activities against GPCR and thus can be effectively used for the prevention and treatment of 5-HT receptor-mediated or muscarinic acetylcholine receptor-mediated diseases.

4-methoxy pyrrole derivatives or salts thereof and pharmaceutical composition comprising the same

The present invention provides tetrahydrocyclopentapyrrole derivatives that can be used for preventing or treating peptic ulcer, gastritis or reflux esophagitis, a method for preparing the same, and a pharmaceutical composition containing the same.

Tetrahydrocyclopentapyrrole derivatives and a method for preparing the same

The present invention relates to novel oxodihydropyridinecarbohydrazide derivatives with excellent antifungal activities, an antifungal composition containing the same, and its use for the prevention and treatment of fungal infectious diseases. The oxodihydropyridinecarbohydrazide derivatives of the present invention have excellent antifungal and fungicidal activities, and thus will be useful for the prevention and treatment of various fungal infections byspp.,spp.,andspp., etc. Additionally, the oxodihydropyridinecarbohydrazide derivatives of the present invention, unlike other fungicidal preparations, can be orally administered.

Antifungal oxodihydropyridinecarbohydrazide derivative

Disclosed are novel triazole derivatives. Exhibiting excellent antifungal activity and in vivo safety, they are useful for the treatment or prevention of fungal infections caused by a wide spectrum of fungi.

Antifungal triazole derivatives

The present invention relates to triazole derivaties, a method for the preparation thereof, and a pharmaceutical composition containing the same as an active ingredient. The inventive triazole derivaties have an excellent antifungal activity against various pathogens.

Antifungal triazole derivatives, method for the preparation thereof and pharmaceutical composition containing same

Disclosed herein are antifungal triazole derivatives or pharmaceutically acceptable salts thereof, a preparation method thereof, and a pharmaceutical composition comprising the same. The triazole derivatives of Chemical Formula 1 or pharmaceutically acceptable salts thereof according to the present invention have excellent inhibitory activity against a broad spectrum of fungi, in addition to being safe to the body, and thus are very useful in the treatment and prevention of fungal infection.

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Gyeonggi-do, South Korea

Mi Ryeong Han