Cartesian Therapeutics, Inc.

Metin Kurtoglu

Murat V Kalayoglu

Michael S Singer

C Andrew Stewart

Yi Zhang

Provided herein are chimeric antigen receptors (CARs), such as those specific for BCMA, that have improved properties, including increased CAR T cell binding to BCMA and improved CAR T cell killing of BCMA-expressing cancer cells. Use of the CARs in immune cells (e.g., T cells), compositions (e.g., CARs and nucleic acid constructs encoding the same), and methods are also contemplated.

Growing community of inventors

Bethesda, MD, United States of America

Metin Kurtoglu