Farmitalia Carlo Erba S.p.a.

Farmitalia Carlo Erba S.r.l.

Farmitalia Carlo Erba

Metilde Buonamici

Alessandro Rossi

Lorenzo Pegrassi

Sergio Mantegani

Lucio Merlini

Enzo Brambilla

Use of ergoline derivatives in treating emesis

Compounds of the formula I ##STR1## wherein R.sub.1 represents a hydrogen atom or a methyl group, either R.sub.2 and R.sub.3 represent hydrogen atoms or together represent a chemical bond, R.sub.4 represents a hydrogen atom or a C.sub.1 -C.sub.4 alkyl group, R.sub.5 represents a C.sub.1 -C.sub.4 alkyl group or an allyl group and R.sub.6 represents a hydrogen or halogen atom, and pharmaceutically acceptable salts thereof, are disclosed as being useful for the treatment of extrapyramidal syndromes such as Parkinson's disease.

Antiparkinson ergoline derivatives

Substituted imino derivatives of 4 H-2, 3-dihydrobenzopyran and 4 H-2, 3-dihydrobenzothiopyran, and pharmaceutical compositions containing them. The compounds are active on the central nervous system, in particular as central nervous system depressants, i.e., sedatives, anticonvulsive agents, tranquilizers and sleep-inducing agents.

Substituted iminoderivatives of dihydrobenzopyran and

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Milan, Italy

Metilde Buonamici