Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.

Hadasit Medical Research Services and Development Ltd.

Other

Mervyn Shapiro

Abraham Domb

Joseph Frucht-Pery

Joseph Frucht-Perry

Provided is a device for iontophoretic delivery of a drug to or into a tissue, including an arrangement that prevents operation of the device at a current density that is higher than a predetermined value, the arrangement including first means responsive to a first data item, indicative of the surface area through which the current is to pass, as to set the maximal current allowed at the surface area indicated by the data item. Also provided is a method for iontophorectivally administering drug to or into a tissue, including determining a maximal allowed level of current density and preventing application of current density above the maximal allowed level.

Safe device for iontophoretic delivery of drugs

The present invention provides a device for iontophoretic delivery of a drug to on into a tissue, comprising an arrangement that prevents operation of the device at a current density that is higher than a predetermined value, the arrangement including first means responsive to a first data item, indicative of the surface area through which the current is to pass, as to set the maximal current allowed at the surface area indicated by the data item. The present invention also provides a method for iontophorectivally administering drug to or into a tissue, comprising determination of a maximal allowed level of current density and preventing application of current density above the maximal allowed level.

The present invention concerns a device ( ) for administration of charged drugs to the eye comprising an applicator with a receiving portion for holding a hydrogel carrier loaded with the drug. The device also comprises an electric current generating element ( ) for generating currents not exceeding 1000 &mgr;Amp coupled to a timing element ( ) which ensures that currents do not last more than 120 secs.

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Jerusalem, Israel

Mervyn Shapiro