Other

University of Minnesota

Mervyn L De Souza

Michael J Sadowsky

Lawrence Philip Wackett

Jeremy S Minshull

This invention relates to the identification of homologs of atrazine chlorohydrolase and the use of these homologs to degrade s-triazine-containing compounds. In particular, this invention includes the identification of homologs of atrazine chlorohydrolase encoded by a DNA fragment having at least 95% homology to the sequence from the nucleic acid sequence beginning at position 236 and ending at position 1655 of SEQ ID NO:1, where the DNA fragment is capable of hybridizing under stringent conditions to SEQ ID NO:1 and has altered catalytic activity as compared with wild-type atrazine chlorohydrolase.

DNA molecules and protein displaying improved triazine compound degrading ability

An isolated and purified DNA molecule, and an isolated and purified protein, that are involved in the degradation of s-triazine compounds (e.g., atrazine) are provided. A method for the purification of this protein is also provided.

Growing community of inventors

Saint Paul, MN, United States of America

Mervyn L De Souza