Dsm IP Assets B.v.

Eastern Virginia Medical School

University of Utah Research Foundation

Dsm Biomedical Inc.

Meredith Roberts Clark

Patrick F Kiser

Robert S Ward

Gustavo F Doncel

Shanger Wang

Li Li

Durgaprasad Chalasani

Jill Schwartz

Timothy J Mccormick

Kavita Gupta

Julie I Jay

Onkar N Singh

Vivek Agrahari

Melissa Peet

A pharmaceutical composition and methods for using the pharmaceutical composition are disclosed. The pharmaceutical composition may include a therapeutically effective amount of one or more antiviral active pharmaceutical ingredients and a pharmaceutically acceptable excipient. The pharmaceutical composition may be a solid dosage form, wherein the solid dosage form provides sustained release of the antiviral active pharmaceutical ingredient when administered as a vaginal or rectal insert.

Pharmaceutical compositions and methods of making on demand solid dosage formulations

An improved long-acting injectable depot suspension formulation of LB displaying progestational effects which overcomes the aggregation and physical instability of LB injectable depot products, and also provides a longer duration of action of at least 4 months. Potential uses of this formulation include but are not limited to contraception and treatment or prevention of progestin/progesterone-sensitive reproductive tract dysfunctions and disorders.

Formulation of long-acting levonorgestrel butanoate injectable depot suspension

Intravaginal drug delivery device comprising at least one pharmaceutically active substance, and a polyurethane copolymer, wherein the copolymer has the structure according to formula (I): Also, method comprising administering one or more pharmaceutically active substances to a patient in need thereof.

Intravaginal ring comprising polyurethane composition for drug delivery

The invention is directed to an intravaginal drug delivery device comprising at least one pharmaceutically active substance, and a polyurethane copolymer, wherein the copolymer has the structure according to formula (I):  The invention is further directed to administering one or more pharmaceutically active substances to a patient in need thereof.

Described herein are polymeric compositions that comprise at least one polymer residue and at least one crosslinking moiety, wherein the polymer residue is crosslinked by the crosslinking moiety and wherein the crosslinking moiety is formed from a reaction between a boronic acid moiety and a hydroxamic acid moiety. Also, described are methods of making and using such polymeric compositions.

Polymeric compositions and methods of making and using thereof

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Bethesda, MD, United States of America

Meredith Roberts Clark