Perfect (china) Co., Ltd.

Shanghai Jiao Tong University

Perfect Company

Menghui Zhang

Liping Zhao

Jing Wang

Xu Zhang

Guang Ning

Xiaojun Zhang

Xiaoying Li

Yifei Zhang

Xiaoyan Pang

Linghua Wang

Guojun Wu

Chenhong Zhang

Yufeng Zhao

Huan Wu

This invention relates to novel probiotic Bifidobacteria strains, particularly,strains, and their use as probiotic, and food products, feed products, dietary supplements and pharmaceutical formulations containing them. The bacteria are suitable for the treatment of obesity, diabetes, and related conditions.

Probioticsstrains

A method in which a microorganism operational taxonomic unit (OTU) in a sample is defined based on a DNA sequence of a system generation information gene of microorganism in the sample. In the method, qualified sequence segments are obtained by means of processing and reading of an original sequence; the segments are sorted according to a relative abundance value of each segment; and only the qualified sequences with the high abundance values are used to obtain the temporary OTU. The qualified sequences with the low abundance values are reallocated; and the qualified sequence can be distributed to the proper temporary OTU respectively when a sequence similarity degree between the qualified sequence and an OTU sequence reaches at least 97%. The present disclosure also provides a sequence-assisted microorganism separation method.

Determination of microorganism operational taxonomic unit and sequence-assisted separation

A method and a composition for improving gut micro biota structure, selectively increase a first gut microbiota population while simultaneously decrease a second gut micro biota population in a subject. The first gut micro biota population includes a short-chain fatty acid (SCFA)-producing bacterium and the second gut microbiota population includes an endotoxin-producing bacterium.

Methods and compositions for improving gut microbiota population

Growing community of inventors

Shanghai, China

Menghui Zhang