Fresenius Medical Care Holdings, Inc.

Melvin D Jensen

Lynn E Jensen

Deloy Lindley

Martin Joseph Crnkovich

Colin Weaver

Venugopal Raghavendra Ghatikar

Mohsen Reihanifam

Kulwinder S Plahey

Thomas Irvin Folden

Michael Emmanuel Kotsos

Joseph Michael Fallon

Venugopal R Ghatikar

The invention provides, in some aspects, a container system for medical solutions such as peritoneal dialysis (PD) solutions. The invention particularly features a system which includes a first compartment that contains a first medical solution, e.g., a PD osmotic agent, and a second compartment that contains a second medical solution, e.g., a PD buffer agent. The compartments maintain their respective contents separately from one another for purposes of transport, storage and/or sterilization. However, the compartments are fluidly couplable, so that their respective contents can be combined with one another, e.g., following sterilization of the agents and prior to their introduction into the patient's abdomen. To that end, a container system can include a diffuser that is disposed in a fluid pathway between the first and second compartments, e.g., to facilitate homogeneous mixing of the first and second PD agents. That diffuser is disposed within and moves relative to a structure, such as a port that defines the fluid pathway between those compartment. Thus, for example, the diffuser can comprise a body that 'floats' within that pathway-defining structure and that moves from one end to the other (and/or to from points there between), depending on a direction of solution flow through the structure.

Systems and methods for delivery of peritoneal dialysis (PD) solutions with integrated inter-chamber diffuser

A male luer connector includes a body having a first end configured to be connected to a fluid line, a second end opposed to the first end, and a body longitudinal axis. The second end is configured to be inserted into and form a luer slip connection with a female luer connector. The male luer connector also includes a locking collar that is connected to the body in a manner such that the locking collar rotates about the longitudinal axis. In some cases, the body second end does not protrude beyond a plane that is transverse to the longitudinal axis and that includes an end face of the locking collar, and/or when male and female connectors are engaged, the locking collar engages an outer surface of the female fluid line connector and is deformed by the engagement.

Fluid line connectors

Systems and methods for delivery of peritoneal dialysis (PD) solutions with integrated inter chamber diffuser

A medical fluid delivery cassette configured for use with a medical fluid pumping system and related systems and methods. The medical fluid delivery cassette includes a base and a membrane that together define a fluid pump chamber. The medical fluid delivery cassette further includes a member configured to apply an outward force to an inner surface of the membrane.

Medical fluid cassettes and related systems and methods

A cassette is described for holding circuit components used with a hemodialysis machine.

Dialysis systems and related components

In general, this disclosure relates to extracorporeal fluid circuits. In some aspects, an air-release device for allowing air to be released from a liquid in extracorporeal circuitry includes an elongate chamber having a bottom region and a top region and a fluid entry port and fluid exit port at or near the bottom region. The air release device also includes a vent structure at or near the top region of the elongate chamber that includes a porous material capable of swelling when moistened such that the vent structure can inhibit liquid from escaping the air-release device during use.

Safety vent structure for extracorporeal circuit

A vent assembly is described for use in an extracorporeal fluid unit. A vent structure adjacent to a micro-porous membrane forms the assembly. The vent structure is porous, but expands when the vent structure becomes wet, thereby closing off the pores and inhibiting (e.g., preventing) fluid from flowing through the vent structure. The vent structure also protects the membrane from becoming wet, such as from condensation.

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West Haven, UT, United States of America

Melvin D Jensen