Glaxo Wellcome Inc.

Melissa Williams Lowery

Francis Gerard Fang

Shiping Xie

Method of removing heavy metal contaminants from organic compounds

A process of providing novel compounds of Formula (I) below, which are useful as intermediates in the preparation of camptothecin and camptothecin-like compounds, ##STR1## wherein: R.sup.1 represents alkyl, particularly methyl, R.sup.2 represents H or alkyl, particularly methyl, R3 represents H or alkyl, particularly H; Q represents triflate or halo particularly bromo and iodo more particularly iodo and Y represents H, chloro or OR.sup.4, wherein R.sup.4 represents alkyl or triflate, or particularly H.

Growing community of inventors

Raleigh, NC, United States of America

Melissa Williams Lowery