The University of British Columbia

Melissa H Brown

Robert E Hancock

Kevin L Piers

Niamh Kelly

A method for the microbial production of a cationic peptide having anti-microbial activity is provided, wherein the cationic peptide is first produced as a fusion protein having an anionic portion for suppressing the antimicrobial activity of the cationic portion. A novel cationic peptide having anti-microbial activity and LPS-binding activity is also provided. Such peptides are useful for suppressing the growth of bacteria and for the treatment of endotoxemia-associated disorders.

Treatment of endotoxin-associated disorders with cationic peptides

Method for recombinant production of cationic peptides and a novel polycationic antibacterial peptide.

CEMA cationic peptide and polynucleotides encoding cEMA

A method for the microbial production of a cationic peptide having anti-microbial activity is provided, wherein the cationic peptide is first produced as a fusion protein having an anionic portion for suppressing the antimicrobial activity of the cationic portion. A novel cationic peptide having anti-microbial activity is also provided.

Growing community of inventors

Vancouver, Canada

Melissa H Brown