University of Illinois

Genalyte, Inc.

Melinda S McClellan

Lawrence Cary Gunn, Iii

Martin Anthony Gleeson

Matthew S Luchansky

Ryan C Bailey

Abraham J Qavi

Jared T Kindt

Tate Owen

Ji-Yeon Byeon

Adam L Washburn

Ryan C Balley

Lawrence C Gunn

Various embodiments are drawn to systems and methods for detecting an analyte of interest in a sample including an optical sensor, a capture probe attached to a surface of the optical sensor wherein the capture probe is capable of binding to the analyte to form a duplex or complex, and an antibody capable of binding to the analyte, duplex, or complex. In several embodiments, systems and methods further include a particle attached to the antibody or capable of binding to the antibody. In several embodiments, systems and methods for analyte detection feature one or more of the following: high detection sensitivity and specificity, scalability and multiplex capacity, ability to analyze large analytes, and ability to detect or measure multiple individual binding events in real-time.

Optical analyte detection systems and methods of use

Growing community of inventors

Champaign, IL, United States of America

Melinda S McClellan