Henkel Ag & Company, Kgaa

Melanie Giesen

Christian Kropf

Thorsten Knappe

Erik Schulze Zur Wiesche

Thomas Doering

Ursula Huchel

Bernhard Banowski

Astrid Kleen

Mustafa Akram

Thomas Welss

Andreas Bock

Natascha Schevardo

Kristin Miehlich

Thomas Döring

Patricia Klaka

Sabine Gruedl

Peter Brenneisen

Philipp Spuhler

Lars Vierkotten

Helen Walter

Guido Fuhrmann

Edo Hoting

Jennifer Evening

Sabine GRÜDL

Thomas Welß

Olaf Holtkötter

Benedikt Schmitz

Dirk Petersohn

Johanna Fromm

Lirija Alili

Klaus Rudolf SCHRÖDER

Thomas Weiss

The present disclosure concerns an in-vitro full skin model which comprises a dermal equivalent and epidermal equivalent as well as from about 1 to about 100 three-dimensional sweat gland equivalents with respectively from about 500 to about 500000 sweat gland cells as well as a diameter of respectively from about 100 to about 6000 &#x3bc;m on a supporting layer. Furthermore, the present disclosure concerns the production of the full skin model as well as the use of this model as an in-vitro model, in screening methods as well as for in-vitro evaluation of the influence of cosmetic substances on the inhibition of sweat secretion as well as body odor.

In-vitro full-skin model containing three-dimensional cell culture models of the sweat gland

The invention relates to a cosmetic composition for bleaching the skin, which includes a) at least one oily plant extract from thegenus and b) at least one ascorbic acid ester. The invention further relates to the cosmetic, nontherapeutic use of the cosmetic composition according to the invention to treat excessive pigmentation, pigmentation disorders, age spots, and/or post-inflammatory hyperpigmentation of the skin, and to a method for producing a cosmetic skin-bleaching composition in the form of an O/W or a W/O emulsion, wherein an oily extract from licorice roots is dissolved in the water phase by the addition of an ascorbic acid ester.

Cosmetic compositions for bleaching the skin

Cosmetic composition comprising at least one compound from advanced glycation end products ('AGEs') and/or precursors thereof as an agent for skin treatment, especially for protection and/or care of the skin. The present invention further provides a cosmetic composition comprising at least one compound from the group of the AGEs and/or precursors thereof, wherein the AGEs are prepared by reacting sugars with the amino acids lysine and/or arginine.

Advanced glycation end products as active ingredients

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Geldern, Germany

Melanie Giesen