California Institute of Technology

Dartmouth College

Meisam Honarvar Nazari

Axel Scherer

Muhammad Mujeeb-U-Rahman

Mehmet Sencan

Arti Gaur

Saman Saeedi

Azita Emami-Neyestanak

A fully integrated small size implantable sensing device is described, which can include a sensor and an electronic circuit to interface with the sensor and communicate with an external device. Various fabrication methods for the sensing device are described, including provision of wells, created using same fabrication technology as the electronic circuit, to contain electrodes of the sensor and corresponding functionalization chemicals. Such implantable sensing device can be used for a variety of electrochemical measuring applications within a living body as well as actuation by injecting a current into the living body.

System and methods for wireless drug delivery on command

A sensor incorporates one or more working electrodes, a counter electrode and a reference electrode. The sensor is inserted in a needle and connected to control electronics to detect the concentration of target molecules. The electrodes are arrays of nanostructures increasing the detection surface area. The nanostructures are functionalized with nucleic acids which bind to select target molecules.

Integrated electrochemical nucleic acid based sensors and related platforms

A receiver architecture is disclosed which employs an RC double-sampling front-end and dynamic offset modulation technique. A low-voltage double-sampling technique provides high power efficiency by avoiding linear high-gain elements conventionally employed in typical transimpedance-amplifier (TIA) receivers. In addition, a demultiplexed output of the receiver helps save power in the subsequent digital blocks. Various applications are described including optical receivers, electrical on-chip interconnects, as well as pulse amplitude modulation. The receiver can be implemented in CMOS and is scalable and portable to other technologies.

Double-sampling receiver with dynamic offset modulation for optical and electrical signaling

Fabrication of implantable fully integrated electrochemical sensors

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Pasadena, CA, United States of America

Meisam Honarvar Nazari