Immuron Limited

Hadasit Medical Research Services and Development Ltd.

Meir Mizrahi

Yaron Ilan

Ami Ben-Ya'Acov

Gadi Lalazar

Tomer Adar

Ami Ben-Ya'acov

This invention relates to methods and compositions for treating fibrosis, by administering compositions comprising anti-LPS immunoglobulin enriched colostrum preparations. In particular, the invention relates to methods and compositions for the treatment of liver fibrosis and/or lung fibrosis. Prophylactic or therapeutic compositions and diagnostic methods are also disclosed and claimed.

Anti-LPS enriched immunoglobulin for use in treatment and/or prophylaxis of fibrosis

The invention relates to the use of preparations enriched with anti LPS antibodies, such as those derived from mammalian colostrum or avian eggs, and optionally further antibodies against disease-associated antigens, colostrums, milk or milk product component/s and any adjuvants for treating, delaying or preventing the progression of a pathologic disorder such as chronic liver disease, cirrhosis and any complication or disorder associated therewith. The invention further relates to combined compositions comprising a combination of anti-LPS enriched antibody preparations and antibodies recognizing at least one antigen specific for a pathologic disorder and uses thereof in the treatment of immune-related disorders.

Anti-LPS enriched immunoglobulin preparations for the treatment and/or prophylaxis of a pathologic disorder

Methods and compositions for treating conditions including liver dysfunction, e.g., associated with fatty liver; glucose intolerance; and others, by administering compositions comprising anti-LPS immunoglobulin enriched colostrum preparations.

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Modiin, Israel

Meir Mizrahi