Edwards Lifesciences Innovation (israel) Ltd.

Meir Kutzik

Boaz Manash

Tal Sheps

Yaron Herman

Ehud Aviv

Or Cohen

Eran Hoffer

Sarit Avivi

A radiopaque frame is transluminally advanced to an atrium of a heart of a subject. The frame is expanded within a valve adjacent the atrium such that part of the frame remains disposed in the atrium. While the frame remains expanded within the valve, progressive portions of an annuloplasty structure are progressively positioned and anchored around the annulus using multiple anchors by, for each of the anchors sequentially (i) while fluoroscopically imaging the frame and a distal end of a delivery tool, and facilitated by mechanical guidance from the frame, positioning the distal end of the delivery tool between the frame and a wall of the atrium; and (ii) driving the anchor into the annulus laterally from the frame. Subsequently, the frame is contracted and withdrawn from the subject while leaving the annuloplasty structure anchored around the annulus. Other embodiments are also described.

Fluoroscopic visualization of heart valve anatomy

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Kafir Saba, Israel

Meir Kutzik