Nanopass Technologies Ltd.

Q-flo Limited

Nanopass Ltd.

Meir Hefetz

Yehoshua Yeshurun

Yotam Levin

Meint De Boer

Gilad Lavi

Yoel Sefi

Adam Meyer Boies

Martin Pick

J W Berenschot

J G E Gardeniers

Jacob John Swanson

Liron Issman

Ortal Tiurin

Sahar Tenenbaum

Sean Howard

Jeronimo Terrones Portas

Victor Halperin

Erwin Berenschot

Garrit Boom

Dominique Maria Altpeter

Gil Fruchtman

Jge Gardeniers

Jw Berenschot

Christian Hoecker

Fiona Ruth Smail

J G Gardeniers

Yehushua Yeshurun

The present invention relates to an electromagnetic waveguide comprising an electromagnetic interference shielding gasket which includes a self-supporting body of non-woven carbon nanotubes adapted to incorporate one or more apertures and to the electromagnetic interference shielding gasket per se.

Electromagnetic waveguide with an EMI shielding gasket

A system and method for delivering fluid into a flexible biological barrier employs a microneedle structure wherein a final position of microneedles () inserted into the biological barrier () is generally sideways projecting from the delivery configuration instead of the conventional downwards projecting arrangement. The microneedles () project from a relief surface () which is distinct from a primary biological-barrier contact region () of the delivery configuration, and is typically angled upwards away from the biological barrier. During insertion, the contact region () is brought into contact with the biological barrier () and moved parallel to the surface of the flexible biological barrier so as to generate a boundary () between a stretched portion () and a non-stretched portion () of the barrier. Typically concurrently with this motion, the microneedles () penetrate into the flexible biological barrier such that, at the end of the motion, the microneedles extend into the flexible biological barrier from the boundary region () in a direction towards the non-stretched portion (). Fluid is then injected through the bores of the hollow microneedles towards non-stretched portion.

System and method for delivering fluid into flexible biological barrier

A system and method for delivering fluid into a flexible biological barrier employs a microneedle structure wherein a final position of microneedles inserted into the biological barrier is generally sideways projecting from the delivery configuration instead of the conventional downwards projecting arrangement. The microneedles project from a relief surface which is distinct from a primary biological-barrier contact region of the delivery configuration, and is typically angled upwards away from the biological barrier. During insertion, the contact region is brought into contact with the biological barrier and moved parallel to the surface of the flexible biological barrier so as to generate a boundary between a stretched portion and a non-stretched portion of the barrier. Typically concurrently with this motion, the microneedles penetrate into the flexible biological barrier such that, at the end of the motion, the microneedles extend into the flexible biological barrier from the boundary region in a direction towards the non-stretched portion. Fluid is then injected through the bores of the hollow microneedles towards non-stretched portion.

A method for processing a wafer to form a plurality of hollow microneedles projecting from a substrate includes forming, by use of a dry etching process, a number of groups of recessed features, each including at least one slot deployed to form an open shape having an included area and at least one hole located within the included area. The internal surfaces of the holes and the slots are then coated with a protective layer. An anisotropic wet etching process is then performed in such a manner as to remove material from outside the included areas while leaving a projecting feature within each of the included areas. The protective layer is then removed to reveal the microneedles.

Microneedle structure and production method therefor

A device () and method for transporting fluids across biological barriers enhances penetration of a biological barrier by the use of directional insertion, preferably with asymmetric microneedles () and/or microneedles () with sharp edges. Additionally, or alternatively, adhesion followed by alteration of contact geometry is employed to stretch the biological barrier across the microneedles (), thereby also enhancing penetration. Also disclosed is a device () and method which combine shallow penetration by hollow microneedles () with jet injection via the microneedles () to achieve a total liquid penetration depth greater than the mechanical penetration depth of the microneedles ().

Devices and methods for transporting fluid across a biological barrier

A method for producing microneedles. The method including disposing a first layer of a radiation sensitive polymer on to a working surface and selectively irradiating the first layer such that the first layer has at least one irradiated region and at least one non-irradiated region. The method also including developing the first layer so as to selectively remove one of the at least one irradiated region and the at least one non-irradiated region such that, at least part of at least one remaining region at least partially defines a form of at least part of a microneedle structure. A microneedle structure including a plurality of microneedles at least partially formed from a radiation sensitive polymer.

Polymer microneedles

Growing community of inventors

Mizpeh Harashim, Israel

Meir Hefetz