Lifebond Ltd

Biota, Inc.

Meir Haber

Ishay Attar

Natalie Iram

Chagai Komlos

Orahn Preiss Bloom

Orahn Preiss-Bloom

Thordis Kristmundsdottir

Skuli Skulason

Revital Mashal

Michal Sanchik

The invention relates to an orally administrable mucoadhesive film which comprises one or more bioactive ingredients and, as a major film-forming polymer, at least one alginate which is capable of forming a low viscosity aqueous solution. Also provided is a process for preparing such films.

Orally administrable films and preparation thereof

Improved compositions comprising a cross-linkable protein or polypeptide, and a non-toxic material which induces cross-linking of the cross-linkable protein. The compositions are optionally and preferably prepared in a non-phosphate buffer solvent. Optionally and preferably, the cross-linkable protein includes gelatin and any gelatin variant or variant protein as described herein. Optionally and preferably, the non-toxic material comprises transglutaminase (TG), which may optionally comprise any type of calcium dependent or independent transglutaminase, which may for example optionally be a microbial transglutaminase (mTG).

Cross-linked compositions

Growing community of inventors

Or Akiva, Israel

Meir Haber