Sanofi-a Ventis Deutschland Gmbh

Meinolf Werner

Olaf Zeckai

Michael Schabbach

Philippe Nzike

Ole Simonowsky

Tobias Stever

Ulrik Jakobi

Nils Basso

Ngoc-Jane Lam

Bernd Petermann

The present invention relates to a disposable delivery assembly for a drug delivery device to dispense a liquid medicament, the delivery assembly comprising:

Disposable delivery assembly for a drug delivery device

A disposable cartridge for a drug delivery device includes a flexible bag to accommodate a liquid medicament and having an opening adjacent to a sidewall, a socket having a fluid channel in fluid communication with a cartridge fluid coupling, and a housing covering at least a portion of the flexible bag and having a receptacle to receive the socket with the flexible bag. The socket extends into the opening of the flexible bag. The flexible bag's sidewall is fixed between the socket and the receptacle.

Disposable cartridge for a drug delivery device

The present invention relates to a disposable delivery assembly for a drug delivery device to dispense a liquid medicament, the delivery assembly comprising: a disposable injector () comprising an injection needle (), a flexible tube () and an injector fluid coupling (), wherein the injection needle () is in fluid communication with the fluid coupling () via the flexible tube (), a disposable cartridge () comprising a reservoir () at least partially filled with the liquid medicament and comprising a cartridge fluid coupling () in fluid communication with the reservoir (), wherein the injector () and the cartridge () are mechanically interconnected in an undeployed configuration (), in which the injector fluid coupling () and the cartridge fluid coupling () are disconnected, and&#x2014;wherein the cartridge () is displaceable relative to the injector () into a deployed configuration (), in which the injector fluid coupling () and the cartridge fluid coupling () are in fluid communication.

The present invention relates to a drug delivery device for dispensing a liquid medicament, comprising: a housing () having at least one feeder member (), a disposable injector () comprising an injection needle (), a flexible tube () and an injector fluid coupling (), wherein the injection needle () is in fluid communication with the fluid coupling () via the flexible tube (), a disposable cartridge () comprising a reservoir () at least partially filled with the liquid medicament and comprising a cartridge fluid coupling () in fluid communication with the reservoir (), wherein the injector () and the cartridge () are releasably attachable to the housing () and arrestable to the housing () in an undeployed configuration (), in which the injector fluid coupling () and the cartridge fluid coupling () are disconnected, and wherein one of injector () and cartridge () is displaceable relative to the other one of injector () and cartridge () from the undeployed configuration () into the deployed configuration () while attached to the housing (), wherein when in deployed configuration the injector fluid coupling () and the cartridge fluid coupling () are in fluid communication.

Drug delivery device with disposable cartridge and disposable injector

A peristaltic pump comprises a tube for transporting a material, wherein the tube is arranged linearly along a longitudinal axis. The peristaltic pump further comprises a pump head for causing a squeezing of the tube, wherein the pump head is rotatable about a rotation axis.

Peristaltic pump

A peristaltic pump comprises a tube to transport a material in a transport direction and one or more piezoelements, which are configured to cause a squeezing of the tube. Furthermore, a method of transporting material comprises the step of successively actuating the piezoelements along the transport direction of the material and thereby causing a squeezing of the tube.

Peristaltic pump and method of transporting material with a peristaltic pump

The invention relates to a drive mechanism () for a needle insertion arrangement (), the drive mechanism () including:&#x2014;a cross beam () linearly movable in a distal direction (D) and a proximal direction (P) for moving an injection needle (),&#x2014;an actuator (),&#x2014;a slider () coupled to the actuator () and linearly movable in a transversal direction (T) at right angles relative the distal direction D and the proximal direction D,&#x2014;a cam () on one of the cross beam () and the slider (),&#x2014;a guide track () in the other one of the cross beam () and the slider () adapted to engage the cam (), the guide track including a sloped section () such that the cross beam () is moved on movement of the slider ().

Drive mechanism for a needle insertion arrangement

The invention relates to a drive mechanism () for a needle insertion arrangement (), the drive mechanism () comprising a rotatable wheel () with a notch () having a closed curve geometry comprising a curved section () and a linear section (), wherein at least one cross beam () is movably arranged and engageable to an injection needle () to move it between a retracted position (RP) and an extended position (EP), wherein the cross beam () comprises a cam () adapted to engage the notch ().

A peristaltic pump comprises a tube to transport a material in a transport direction and a conveying screw, which is configured to cause a transport of the material by causing a successive squeezing of the tube along the transport direction.

The invention relates to a drive mechanism () for a needle insertion arrangement (), the drive mechanism () comprising an actuator () coupled to a parallel linkage () adapted to convert a linear movement of the actuator () in a longitudinal direction (L) to a linear movement of a cross beam () in transverse direction (T) substantially at right angles with respect to the longitudinal direction (L).

The invention relates to a drive mechanism () for a needle insertion arrangement (), the drive mechanism () being arranged as a bistable mechanism with at least one pivoted link () having two stable end positions (LEP, UEP) and an instable transitional central position (CP), the drive mechanism () further comprising a spring () biasing the link () out of the transitional central position (CP), wherein at least one trigger unit () is arranged for moving the link () out of at least one of the stable end positions (LEP, UEP) towards and beyond the transitional central position (CP) against the bias of the spring ().

The invention relates to a drive mechanism () for a needle insertion arrangement (), the drive mechanism () comprising: &#x2014;an actuator (), &#x2014;a needle retainer () adapted to retain an injection needle () and linearly movable in a distal direction (D) and a proximal direction (P) for moving an injection needle (), &#x2014;a cam () arranged on or coupled to the needle retainer (), &#x2014;a guide curve () adapted to be rotated by the actuator () about an axis () aligned in the distal direction (D) and the proximal direction (P) and adapted to engage the cam (), wherein the guide curve () comprises a sloped section () such that the needle retainer () is moved on rotation of the guide curve ().

The invention relates to a drive mechanism for a needle insertion arrangement, the drive mechanism comprising: an actuator, a rotatable drive pulley directly or indirectly coupled to the actuator, and a belt adapted to engage the drive pulley and adapted to be fixed to a needle retainer.

Disclosed is a needle insertion arrangement () with a drive mechanism () comprising: a belt () frictionally engaging a first roller () and a needle retainer () with an injection needle () fixed to the belt, the first roller being rotatably arranged about an axis (A), a second roller () also rotatably arranged about the axis (A), a first spring () rotatably biasing the first roller against the second roller, a second spring () rotatably biasing the second roller against an arrester (), the first and the second roller being connected via an internal protrusion () and arcuate slot (), the two springs () biasing the rollers () from respective first to respective second angular positions (AP, AP, AP, AP), and a trigger mechanism () releasably locking the first and second rollers () such that upon pivoting the trigger button () in one direction, the first roller drives the belt in one direction to linearly transport the needle retainer towards an extended position, and upon pivoting the trigger button in the other direction, the first roller drives the belt back to retract the needle retainer.

Needle insertion and retraction arrangment with manually triggered, spring-loaded drive mechanism

A reservoir assembly comprising a reservoir housing, a piston, and a locking plug, both movably arranged inside the reservoir housing; wherein the volume between the piston and the locking plug defines a reservoir cavity. The reservoir assembly further comprising a reservoir outlet; and an actuator configured to act on the piston; wherein the locking plug is configured to be movable from a first position to a second position; wherein in the first position the reservoir outlet is not in fluid communication with the reservoir cavity. The reservoir assembly further comprising an interlock configured to prevent movement of at least one of the locking plug and the piston; wherein the interlock having a locked position and an unlocked position.

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Worms, Germany

Meinolf Werner