East China University of Science and Technology

Meiling Zhao

Juan Li

Yao Lu

Weihong Zhu

Yutao Zhang

Zhiqian Guo

Xiuyan Zhao

Chenxu Yan

A luminescent probe and its preparation method and application are provided. The luminescent probe has a steric hindrance group Rof aliphatic hydrocarbon structure such as adamantane or norborneol, a detection group Rof nitrobenzyl and its derivative structure, an electron-withdrawing group Rcontaining cyano group and an electron-donating group methoxy group. In the presence of HSA or BSA, the detection group is cut off to form a parent structure that exposes atomic oxygen anions and is activated under external light irradiation, the luminescent probe can be used in solution or cells, when detecting HSA or BSA, the luminescent probe has obvious chemiluminescence characteristics, which can sensitively distinguish HSA and BSA, quantitatively analyze HSA and BSA, and determine the mixing ratio of HSA and BSA at the same time, and the luminescent probe has been successfully used for cell fluorescence imaging.

Luminescent probe and its preparation method and application

Growing community of inventors

Shanghai, China

Meiling Zhao