Wilmar (shanghai) Biotechnology Research & Development Center Co., Ltd.

Meifeng Zhou

Wei Wu

Qiwen Niu

Haisheng Cao

Xiaojun Dai

Provided is amutant strain for expressing an exogenous gene. Specifically, provided is amutant strain comprising, with respect tomutant strain GS115 or CICC32806, one or more of the following six mutations: BQ9382_C1-2260, EKK deletions at positions 308-310, a hypothetical protein; BQ9382_C1-3800, E129K, 60S ribosomal subunit assembly/exported protein LOC1; BQ9382_C1-5700, 1312M, mitochondrial external NADH dehydrogenase, type II NAD(P)H: quinone oxidoreductase; BQ9382_C2-3950, Q145X, an essential protein having a binding partner Psr1p and used for completely activating a general stress response; BQ9382_C3-2220, E188K, a hypothetical protein; and BQ9382_C3-4370, W196X, orotidine 5\'-phosphate decarboxylase. The providedmutant strain is an effective commonly employed host for exogenous expression, and can efficiently express different proteins, especially phospholipase and lipase.

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Jiaxing, China

Meifeng Zhou