Curagen Corporation

Mei Zhong

Richard August Shimkets

Ferenc L Boldog

Catherine Burgess

Linda L Gorman

Denise M Lepley

Daniel K Rieger

Carol E A Pena

Henri Lichenstein

Meijia Yang

Kimberly Spytek

John R MacDougall

Michael Jeffers

Muralidhara Padigaru

John L Herrmann

Meera Patturajan

Sudhirdas K Prayaga

William LaRochelle

William Grosse

Stacie Casman

Shlomit Edinger

Corine A M Vernet

Esha A Gangolli

John P Alsobrook, Ii

Elma Fernandes

Edward Voss

Xiaojia Guo

John Peyman

David W Anderson

Glennda Smithson

John P Alsobrook Ii

Nikolai Khramtsov

The present invention provides FGF-CX, a novel isolated polypeptide, as well as a polynucleotide encoding FGF-CX and antibodies that immunospecifically bind to FGF-CX or any derivative, variant, mutant, or fragment of the FGF-CX polypeptide, polynucleotide or antibody. The invention additionally provides methods in which the FGF-CX polypeptide, polynucleotide and antibody are used in detection and treatment of a broad range of pathological states, as well as other uses.

Polypeptides of FGF-CX

Disclosed herein are nucleic acid sequences that encode G-coupled protein-receptor related polypeptides. Also disclosed are polypeptides encoded by these nucleic acid sequences, and antibodies, which immunospecifically-bind to the polypeptide, as well as derivatives, variants, mutants, or fragments of the aforementioned polypeptide, polynucleotide, or antibody. The invention further discloses therapeutic, diagnostic and research methods for diagnosis, treatment, and prevention of disorders involving any one of these novel human nucleic acids and proteins.

Therapeutic polypeptides, nucleic acids encoding same, and methods of use

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Branford, CT, United States of America

Mei Zhong