University of Connecticut

Teleflex Medical, Inc.

Mei Wei

Haibo Qu

James R Olson

Xiaohua Yu

Montgomery T Shaw

Zengmin Xia

Fei Peng

Zhi-kang Xu

A bone-repair composite includes a core and a sheath. The core is a first primary unit including a combination of a first set of yarns coated with a calcium phosphate mineral layer. The first set of yarns being made from a first group of one or more polymers. The sheath is a second primary unit a combination of a second set of yarns or one or more polymer coatings. The second set of yarns being made from a second group of one or more polymers, wherein the composite is made by covering the core with the sheath, and the composite is compression molded to allow the sheath to bond to the core. The bone-repair composite has a bending modulus comparable to that of a mammalian bone, such that the ratio of the core to the sheath is provided to maximize the mechanical strength of the bone-repair composite to mimic the mammalian bone.

Calcium phosphate polymer composite and method

Ceramic/structural protein composite scaffolds and their preparation in a simple one-step process are shown.

Calcium phosphate/structural protein composites and method of preparation thereof

Described herein are novel methods of producing collagen-apatite (Col-Ap) scaffolds that exhibit a unique, anisotropic multi-level lamellar structure in which nano and submicron pores in each lamellae and macro pores are co-aligned.

Biomimetic scaffold for bone regeneration

Ceramic/structural protein composites and methods of preparation are disclosed, including coatings and films. Ceramic/structural protein coatings can be fabricated on the surface of substrates, including the surface of implantable medical devices.

Ceramic/structural protein composites and method of preparation thereof

A ceramic coating with gradient density/porosity and/or incorporated biologically active agents can be fabricated on the surface of substrates, including the surface of implantable medical devices.

Ceramic coating and method of preparation thereof

An artificial bone composite structure is provided. This structure includes a fibrous matrix that itself includes a plurality of fibers. Also, the structure includes a plurality of hydroxyapatite (HA) particles. These particles are dispersed within the fibrous matrix. Also, the HA particles have controlled size and aspect ratios and are aligned along long axes of the fibers. In some instances, the fibers include poly-(L-lactic acid) (PLLA).

Growing community of inventors

Coventry, CT, United States of America

Mei Wei