Bgi Shenzhen

Mgi Tech Co., Ltd.

Huawei Technologies Co., Limited

Shenzhen Deren Electronic Co., Ltd.

Shenzhen Lonnai Technology Co., Ltd.

Mei Li

Wei Chen

Jian Wang

Yu-Xiang Li

Xun Xu

Yi-Wen Liu

Wenwei Zhang

Fan Zhou

Dong Wei

Zhudong Huo

Bingwu Ji

Ming Ni

Yu Xia

Weimao Wang

Yiwen Liu

Mengzhe Shen

Yuxiang Li

Jin-jin Shen

Da-wei Li

Ge Feng

Yang-bao Liu

Jielei Ni

Zeyu Su

Yuanqing Liang

Ke Ji

Wenwei Zhan

Provided are a magnetic bead-based detection method, a storage medium, and a detection device. The detection method includes: collecting a white light image of a to-be-detected solution, in which the to-be-detected solution is mixed with a to-be-detected sample and magnetic beads with a capture agent (S); determining magnetic stripe regions in the white light image, and determining first magnetic bead regions based on the magnetic stripe regions (S); selecting, by using a first neural network, second magnetic bead regions containing magnetic beads from the first magnetic bead regions, and obtaining a marker position of each of the magnetic beads (S); and obtaining, by using a second neural network and based on each of the second magnetic bead regions, codes at code bits of a corresponding magnetic bead, and obtaining corresponding code information based on the codes of the code bits and the marker position of the magnetic bead (S).

Magnetic bead-based detection method, storage medium, and detection device

Disclosed are a super-resolution imaging system (), a super-resolution imaging method, a biological sample identification system () and method, a nucleic acid sequencing imaging system () and method, and a nucleic acid identification system () and method. The super-resolution imaging system () includes an illumination system (A) and an imaging system (B). The illumination system (A) outputs excitation light to irradiate a biological sample to generate excited light, and the imaging system (B) collects and records the excited light to generate an excited light image. The illumination system (A) includes an excitation light source () and a structured light generation and modulation device (). The excitation light source () outputs the excitation light, and the structured light generation and modulation device () modulates the excitation light into structured light to irradiate the biological sample to generate the excited light.

Super-resolution imaging system and method, and nucleic acid sequencing imaging system and method

A fluorescence image registration method includes obtaining at least one fluorescence image of a biochip. An interior local area is selected. Sums of pixel values in the interior local area along a first direction and a second direction are obtained. A plurality of first template lines is selected to find a minimum total value of the sums of pixel values corresponding to the first template lines. Pixel-level correction is performed on a local area of the track line to obtain pixel-level track cross. Other track crosses on the biochip is obtained, and the pixel-level correction is performed on the other track crosses. The position of the pixel-level track line is corrected by a center-of-gravity method to obtain the subpixel-level position of the track line. The subpixel-level positions of all sites uniformly distributed on the biochip is obtained.

Fluorescence image registration method, gene sequencing instrument and system

The present disclosure provides a fluorescence image registration method, the method includes: acquiring a fluorescence image of a biochip; selecting a preset local region of the fluorescence image; acquiring a position of a minimum value of a sum of brightness values of pixels in a first direction and a second direction, and obtaining pixel-level registration points; dividing the pixel-level registration points into non-defective pixels and defective pixels; if the fluorescence image meets the preset standard, correcting positions of the defective pixels according to positions of the non-defective pixels; acquiring a position of a center of gravity of image points of fluorescent molecules according to a center of gravity method; fitting straight lines in the first direction and the second direction respectively according to the position of the center of gravity; and acquiring boundary points of the fluorescence image and calculating the positions of the boundary points.

Fluorescence image registration method, gene sequencing instrument, and storage medium

A fluorescence image registration method includes obtaining at least one fluorescence image of a biochip. An interior local area. Sums of pixel values in the interior local area along a first direction and a second direction are obtained. A plurality of first template lines is selected to find a minimum total value of the sums of pixel values corresponding to the first template lines. Pixel-level correction is performed on a local area of the track line to obtain a pixel-level track cross. Other track crosses on the biochip is obtained, and the pixel-level correction is performed on the other track crosses. The position of the pixel-level track line is corrected by a center-of-gravity method to obtain the subpixel-level position of the track line. The subpixel-level positions of all sites uniformly distributed on the biochip is obtained.

A pet liquid feeding appliance includes an appliance body and multiple feeding assemblies installed at an outer end of the appliance body. The appliance body defines a discharge port for use in conjunction with the feeding assembly, and is further provided with a feeding trough. The feeding assembly includes a fixing piece and a nipple installed at one end of the fixing piece. Both ends of the nipple are each provided with a clamping slot. The fixing piece is provided with a clamping column for use in cooperation with the nipple. The fixing piece and the nipple are detachably connected to each other. One end of the clamping column is provided with a hook, and one end of the fixing piece is provided with a liquid outlet. By providing multiple feeding assemblies, multiple pets can drink together at the same time.

Pet liquid feeding appliance

This application discloses an electrostatic discharge protection apparatus and an integrated circuit with multiple power domains. The electrostatic discharge protection apparatus includes a diode and an NMOS transistor. A positive electrode of the diode is coupled to a first interface, a negative electrode of the diode is coupled to a first electrode of the NMOS transistor, both a second electrode of the NMOS transistor and a gate electrode of the NMOS transistor are coupled to a second interface, and a substrate of the NMOS transistor is used for grounding. At least one electrostatic discharge protection apparatus may be disposed in the integrated circuit with multiple power domains.

Electrostatic discharge protection apparatus and integrated circuit with multiple power domains

An electrical connector includes an insulation body and conductive terminals. The insulation body defines receiving holes corresponding to the conductive terminals, respectively. Each receiving hole includes a first hole portion, a second hole portion and a third hole portion. Each conductive terminal includes a main part, an elastic arm, a connection part, and a holding part. Both the main part and the holding part are embedded in the second hole portion, and are obliquely positioned relative to the X axis of the insulation body. The first and third hole portions are located at two opposite sides of the main part. At least part of the elastic arm is located above the first hole portion.

Electrical connector

Growing community of inventors

Shenzhen, China

Mei Li