Cambridge Enterprise Limited

Smart Holograms Limited

Mei-Ching Lee

Christopher Robin Lowe

Jeffrey Blyth

Satyamoorthy Kabilan

Felicity Kate Sartain

Xiaoping Yang

Abid Hussain

Kathryn Elizabeth Sorrell Medlock

Adrian Martin Horgan

A sensor comprises respective acceptor and donor compounds immobilised in or on a matrix including a glucose-binding boronate and a cationic species, whereby the spacing between the acceptor and donor compounds is reduced in the presence of glucose. For example a holographic sensor comprises a glucose-binding boronate and a cationic species held within the sensor.

Boronate complex and its use in a glucose sensor

A sensor for the detection of an analyte comprising a cis-diol moiety, which comprises a holographic element comprising a medium and a hologram disposed throughout the volume of the medium, wherein an optical characteristic of the element changes as a result of a variation of a physical property occurring throughout the volume of the medium, and wherein the medium is a polymer comprising a group of formula (I): wherein n is 0, 1, 2, 3 or 4; each X (if present) is independently is an atom or group which, via an electronic effect, promotes formation of a tetrahedral geometry about the boron atom; and Y is a spacer which, when n is 0 or otherwise optionally, is an atom or group which, via an electronic effect, promotes formation of a tetrahedral geometry about the boron atom. Such a sensor may be used for the detection of glucose. 

Holographic sensor

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Middlesex, United Kingdom

Mei-Ching Lee