Columbia University

Youdocs, LLC

Youdocs Beauty, Inc.

Mehmet C Oz

William J Allen

Gerald M Lemole

Juan P Umana

Alan Lotvin

Howard P Levin

Howard R Levin

Michael F Roizen

David M Stern

David J Pinsky

Jennifer L Roizen

Jeffrey D Roizen

Shin Koga

Roman Nowygrod

David A D'Alessandro

An apparatus for the repair of a cardiovascular valve has leaflets comprising a grasper capable of grabbing and co-apting the leaflets of the valve. In a preferred embodiment, the grasper has jaws that grasp and immobilize the leaflets, and then a fastener is inserted to co-apt the leaflets. The apparatus is particularly useful for repairing mitral valves to cure mitral regurgitation.

Method and apparatus for circulatory valve repair

Methods and systems enable healthcare providers to identify metabolites that may cause a medical condition in a patient. The healthcare providers may then use the identified metabolite to identify a probiotic that may affect the regulation of that metabolite. Patient information, such as medical history and diagnosis data may then be used in combination with the identified probiotic to create a personalized medicament for that patient.

Methods and systems for improving human health using targeted probiotics

An objective measure of human QOL is determined by a QOL quantification system. The QOL quantification system comprises a QOL rules engine, a QOL measure datastore, a score data archive, a user computing device, and a network. The QOL measure datastore comprises quantifiable measures of QOL of a QOL factor. The QOL rules engine comprises instructions for receiving user data indicative of a plurality of attributes of a selected QOL factor of the user, obtaining measures of QOL from the QOL measures datastore associated with the selected QOL factor, evaluating the user data against the QOL measures of the selected QOL factor, determining a user score indicative of the QOL of the selected QOL factor of the user, storing the user score in the score data archive, and comparing the user score to a score stored in the score data archive. The QOL rules engine may also suggest change options to one or more QOL factors to improve the user score. The suggested change options may be presented as an ordered listed organized by a relative cost benefit measure.

System and method for determining an objective measure of human quality of life

An objective measure of human beauty is determined by a beauty quantification system. The beauty quantification system comprises a beauty quantification processor, a beauty measure datastore, a beauty score datastore, a user computing device, and a network. The beauty measure datastore comprises quantifiable measures of beauty of a body region. The beauty quantification processor comprises instructions for receiving user data indicative of physical attributes of a selected body region of the user, obtaining measures of beauty from the beauty measures datastore associated with the selected body region, evaluating the user data against the beauty measures of the selected body region, determining a user score indicative of the beauty of the selected body region of the user, storing the user score in the beauty score datastore, and comparing the user score to a score stored in the beauty score datastore. The beauty quantification processor may also suggest enhancements to one or more body regions to improve the user score. The suggested enhancements may be presented as an ordered listed organized by a relative cost benefit measure.

System and method for determining an objective measure of human beauty

An apparatus for the repair of a cardiovascular valve has leaflets comprising a grasper capable of grabbing and co-apting the leaflets of the valve. In a preferred embodiment the grasper has jaws that grasp and immobilize the leaflets, and then a fastener is inserted to co-apt the leaflets. The apparatus is particularly useful for repairing mitral valves to cure mitral regurgitation.

An epicardial cooled stabilizer system is useful for surgical or laparoscopic applications, especially beating heart surgery. The system comprises a stabilizer connected to a cooler/pump where coolant flows into tubing at the distal end of the stabilizer. The tubing is positioned at a surgical site to enhance traction and minimize trauma.

Epicardial cooled stabilizer for beating heart surgery

An apparatus for the repair of a cardiovascular valve having leaflets comprises a grasper capable of grabbing and co-apting the leaflets of the valve. Preferably, the grasper has jaw that grasp, immobilize the leaflets, and then a fastener is inserted to co-apt the leaflets. The apparatus is particularly useful for repairing mitral valves to cure mitral regurgitation.

An aqueous solution for organ preservation or maintenance, which contains: a vasodilator in an amount sufficient to maintain vascular homeostasis; D-glucose in an amount sufficient to support intracellular function and maintenance of cellular bioenergetics; magnesium ions in an amount sufficient to support intracellular function and maintenance of cellular bioenergetics; macromolecules of molecular weight greater than 20,000 daltons in an amount sufficient to maintain endothelial integrity and cellular viability; potassium ions in a concentration greater than about 110 mM; and a buffer in an amount sufficient to maintain the average pH of the organ preservation or maintenance solution during the period of organ preservation at about physiologic pH or above.

Solution for prolonged organ preservation

The present invention provides an aqueous solution for organ preservation or maintenance, including: a vasodilator in an amount sufficient to maintain vascular homeostasis; D-glucose in an amount sufficient to support intracellular function and maintenance of cellular bioenergetics; magnesium ions in an amount sufficient to support intracellular function and maintenance of cellular bioenergetics; macromolecules of molecular weight greater than 20,000 daltons in an amount sufficient to maintain endothelial integrity and cellular viability; potassium ions in a concentration greater than about 110 mM; and a buffer in an amount sufficient to maintain the average pH of the organ preservation or maintenance solution during the period of organ preservation at about the physiologic pH value. The invention also provides a method of preserving or maintaining an organ, including contacting the organ with the solution.

Growing community of inventors

Cliffside Park, NJ, United States of America

Mehmet C Oz