Adolphe Merkle Institute, University of Fribourg

Fresenius Kabi Deutschland Gmbh

Mehdi Jorfi

Christoph Weder

E Johan Foster

Physiologically responsive mechanically adaptive optical fibers that are suitable for optical interfacing with living organisms. The optical fibers are particularly suited for applications in optogenetics. Dry, stiff fibers display a desirable tensile storage modulus and can be readily inserted into biological and in particular cortical tissue. Exposure to conditions encountered in vivo results in reduction, often a drastic reduction in modulus. When coupled with a suitable light source, the construction can be utilized to stimulate neurons in vivo. Methods for producing and utilizing the optical fibers and devices including the optical fibers are disclosed.

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Fribourg, Switzerland

Mehdi Jorfi