Sunovion Pharmaceuticals Inc.

Megumi Maruyama

Seth C Hopkins

Yuki Tsushima

Gerald R Galluppi

Takumi Asada

Siriporn Toongsuwan

Provided are modified release compositions in a solid oral dosage form comprising amisulpride in the form of an unequal mixture of (R)-amisulpride and (S)-amisulpride, or pharmaceutically acceptable salts thereof, where the amount of (R)-amisulpride is greater than the amount of (S)-amisulpride, and medicaments comprising the same used for the treatment of various diseases and disorders, and methods of using same for the treatment of various diseases and disorders, including, but not limited to, dosage regimens. In addition, provided are formulations employing polymorphs of enantiomeric amisulpride.

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Okayama, Japan

Megumi Maruyama