Dai Nippon Printing Co., Ltd.

Astellas Pharma Gmbh

Upstream Bio, Inc.

Takeda Pharmaceutical Company Limited

Megumi Ikeda

Akinori Chikushi

Tadahiro Ishida

Yusuke Narumi

Yuzu Imakura

Kenichiro Kiyoshima

Jumpei Suemitsu

Moe Kohno

Shohei Horiuchi

Tomomi Sato

Provided is a stable pharmaceutical composition, comprising an anti-human TSLP receptor antibody, capable of inhibiting the generation of chemically modified substances, such as deamidated forms and oxidized forms, or degradants or multimers. The pharmaceutical composition comprises an anti-human TSLP receptor antibody, a pharmaceutically acceptable buffer, arginine or a pharmaceutically acceptable salt thereof, and a surfactant.

Pharmaceutical composition comprising anti-human TSLP receptor antibody

Provided is a thermal transfer sheet that can form a good image on both a transfer object made of a polyethylene terephthalate and a transfer object made of a polypropylene, as well as can form an image with high alcohol resistance. The thermal transfer sheet of the present invention includes a substrate, and a transfer layer including a colored layer and an adhesive layer, in which the adhesive layer has a phase-separated structure formed by a polyester and a polyolefin that are incompatible with each other, and in which the percentage of the region formed by one of the polyester and the polyolefin to the total area (100%) of the adhesive layer is 55% or more and 85% or less.

Thermal transfer sheet

Provided is a stable pharmaceutical composition comprising a labeling moiety-anti-human antibody Fab fragment conjugate, and the like. In the pharmaceutical composition comprising a labeling moiety-anti-human antibody Fab fragment conjugate, citric acid, phosphoric acid, 2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acid or trishydroxymethyl aminomethane is added as a buffering agent, sucrose or glycerin is added as a stabilizer, a nonionic surfactant is added, and the pH is adjusted to 6.5 to 7.5. This enables suppression of generation of multimers and insoluble subvisible particles during preservation of the labeling moiety-anti-human antibody Fab fragment conjugate.

Pharmaceutical composition containing tagged site-antihuman antibody fab fragment complex

A thermal transfer sheet is provided, which allows for forming an image favorable to any transfer objects having a poor smoothness or a high smoothness. The thermal transfer sheet according to the present invention includes a substrate, and a transfer layer. The transfer layer includes a release layer, a colorant layer and an adhesive layer. The release layer includes a polyethylene glycol having a number average molecular weight Mn in a range of 8000 or more to 23000 or less, and the colorant layer includes a colorant and a vinyl chloride-vinyl acetate copolymer.

Provided is a stable pharmaceutical composition comprising an anti-human TSLP receptor antibody, capable of inhibiting the generation of chemically modified substances, such as deamidated forms and oxidized forms, or degradants, or multimers. The pharmaceutical composition comprises an anti-human TSLP receptor antibody, a pharmaceutically acceptable buffer, arginine or a pharmaceutically acceptable salt thereof, and a surfactant.

Growing community of inventors

Chuo-ku, Japan

Megumi Ikeda