Singular Genomics Systems, Inc.

Megha Cila

Ronald J Graham

Rodrigo Rodriguez

Olga Adelfinskaya

Eli N Glezer

Abrehet Abdu

Ada Tong

Disclosed herein, inter alia, are silicon containing detectable compounds and methods of use thereof. In an aspect is provided a monovalent nucleotide or monovalent nucleoside covalently bound to a monovalent form of a compound described herein (e.g., wherein the R13 moiety of a compound described herein has reacted with a bioconjugate reactive group to form a bioconjugate linker thereby covalently bonding the monovalent compound to the monovalent nucleotide or monovalent nucleoside).

Silicon containing detectable compounds and uses thereof

Disclosed herein, inter alia, are fluorescent compounds and methods of making and using thereof.

Rhodamine fluorescent compounds and production methods thereof

Disclosed herein, inter alia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.

Nucleotide analogues

Disclosed herein, inter alia, are methods and cleavable compounds that minimize byproduct formation following cleavage.

Cleavable disulfide linkers and uses thereof

Disclosed herein, interalia, are compounds, compositions, and methods of using the same for the sequencing of a nucleic acid.

Disclosed herein, inter alia, are compounds, compositions, and methods of use thereof for sequencing a nucleic acid.

Growing community of inventors

San Diego, CA, United States of America

Megha Cila