Autolus Limited

Meggan Czapiga

Shimobi Onuoha

Biao Ma

The invention relates to a method of determining the T cell receptor β chain (TRBC) gene type of a cell, the method comprising (a) determining the J gene type expressed in said cell, and (b) inferring from (a) the TRBC gene type expressed in said cell. The invention further relates to use of a CAR T cell targeted to a T cell receptor β chain (TRBC) type 1, or a CAR T cell targeted to a T cell receptor β chain (TRBC) type 2. The invention further relates to a method of medical treatment, and to nucleic acid probes.

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London, United Kingdom

Meggan Czapiga