The University of North Carolina at Chapel Hill

Md Murad Hossain

Caterina Maria Gallippi

Keita Andrew Yokoyama

Tomasz Joseph Czernuszewicz

Christopher Joseph Moore

Methods, systems, and computer readable media for taking measurements of a material, including determining material anisotropy, are provided. According to one aspect, a method for determining tissue anisotropy comprises: applying, to a tissue sample, a first force having a direction and having a coronal plane normal to the direction of the force, the first force having an oval or other profile with long and short axes within the coronal plane, the long axis being oriented in a first direction within the coronal plane, and measuring a first displacement of the tissue; applying, to the tissue sample, a second force, and measuring a second displacement of the tissue; and calculating a tissue elasticity anisotropy based on the measured first and second displacements. Furthermore, by applying the first and second forces multiple times, tissue viscosity, elasticity, or other anisotropy may be calculated from the multiple displacement measurements.

Methods and systems for assessing material anisotropy and other characteristics

A method for quantitatively measuring a physical characteristic of a material includes performing one or more interrogations of a material sample, each interrogation using a push focal configuration. The method further includes taking measurements of displacement over time of a material sample caused by the one or more interrogations. Each measurement uses an interrogation focal configuration. The method further includes determining a physical characteristic of the material sample based on the measurements of displacement over time of the material sample. According to the method, at least one of the following is true: a tracking focal configuration used for one of the measurements is different from a tracking focal configuration used for another of the measurements; and a push focal configuration used for one of the interrogations is different from a push focal configuration used for another of the interrogations.

Methods, systems, and computer-readable media for nondestructively measuring physical properties of a material by observing induced displacements using different focal configurations

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Chapel Hill, NC, United States of America

Md Murad Hossain