Covidien LP

Tyco Healthcare Group LP

Mbiya Kapiamba

Nadya Belcheva

Amin Elachchabi

Ferass Abuzaina

Ahmad Robert Hadba

Roland Ostapoff

Jack Kennedy

Ahmed Robert Hadba

Ahman R Hadba

Implantable biocompatible polymeric medical devices include a substrate with an acid or base-modified surface which is subsequently modified to include click reactive members.

Medical devices having activated surfaces

Implantable biocompatible polymeric medical devices include a substrate with a plasma-modified surface which is subsequently modified to include click reactive members.

An implantable medical device is disclosed. The medical device includes a substrate and a polymer composition including ascorbic acid, the polymer composition disposed on at least a portion of the substrate.

Polymeric ascorbic acid devices for tissue regeneration

The present disclosure provides for the synthesis of branched polyamines. In embodiments, branched polyamines may be formed by reacting a branched polyol with a nitroaryl carboxylic acid to form a nitrobenzoyl ester which, in turn, may then be subjected to a hydrogenating step to form the branched polyamine. The resulting branched polyamine may then be reacted with another hydrogel precursor to form a hydrogel.

Branched polyamines and formulations thereof for use in medical devices

The disclosure relates to biocompatible components useful for forming compositions for use as medical/surgical synthetic adhesives and sealants. Biocompatible components of the present disclosure may include a polymeric polyol core, which may be treated with a nitroaryl compound to form a nitro ester. The resulting nitro ester groups may be reduced to form amino groups which, in turn, may be treated to form isocyanate groups. The resulting isocyanate may then be reacted with a second component to form adhesive and/or sealant compositions.

Adhesive formulations

The present disclosure provides compositions which may be utilized as adhesives or sealants in medical and surgical applications. The compositions may, in embodiments, be formed from the cycloaddition reaction of a first component possessing at least one azide group with a second component possessing at least one alkyne group.

Growing community of inventors

Cromwell, CT, United States of America

Mbiya Kapiamba