Teva Pharmaceutical Industries Limited

Assia Chemical Industries Ltd.

Teva Pharmaceuticals Usa, Inc.

Other

Maytal Piran

Rotem Sella-Erez

Sharona Shachan-Tov

Leonid Metsger

Doron Rudik

Valerie Niddam-Hildesheim

Vinod Kumar Kansal

Tamas Koltai

Sigalit Levi

Greta Sterimbaum

Hagit Eisen-Nevo

Adi Yeori

Suhail Ahmad

Jacob Rendell

Shay Asis

David Malcolm Crowe

Tamar Nidam

Ariel Mittelman

Zvi Harel

Ofir Shaul

Jonathan Enav

Ido Fuchs

Motti Erlich

Marina Yarovoy

Einat Kisin-Finfer

Jenny Goldshtein

Elvira Haimov

Abed Masarwa

Oshrat Frenkel

Victoria Machtey

Sagit Azran

Vineet Kumar Tyagi

Ayyagari Subramanya Sharma

Rotem Sella-erez

The present disclosure relates to solid state forms of Omecamtiv mecarbil and Omecamtiv mecarbil diHCl, processes for preparation thereof, pharmaceutical compositions thereof, and methods of use thereof.

Solid state forms of Omecamtiv mecarbil and Omecamtiv mecarbil diHCl

The present disclosure encompasses crystalline polymorphs of Pracinostat and of Pracinostat salts, and pharmaceutical compositions thereof.

Crystalline polymorphs of Pracinostat and Pracinostat salts

Salts and solid state forms of Larotrectinib, processes for preparation thereof, pharmaceutical compositions thereof, and uses thereof are disclosed.

Crystalline form E1 of larotrectinib ethanesulfonate

Solid state forms of Valbenazine, Valbenazine salts, processes for preparation thereof and pharmaceutical compositions thereof are disclosed. Processes for the preparation of Valbenazine and intermediates in the preparation thereof are further described.

Solid state forms of valbenazine

Nilotinib salts and crystalline forms thereof have been prepared and characterized.

Nilotinib salts and crystalline forms thereof

New forms of Febuxostat have bean, prepared and characterized. These forms are useful for examples in the chronic management of hyperuricemia in patients with gout.

Crystalline forms of febuxostat

New forms of Febuxostat have been prepared and characterized. These forms are useful, for example, in the chronic management of hyperuricemia in patients with gout.

Crystalline forms of Febuxostat

Crystalline forms of Nilotinib HCl are described.

Nilotinib HCl crystalline forms

Crystalline form of febuxostat

Salts and crystalline forms of several salts of Varenicline, i.e., Varenicline sulfate: are provided, along with methods of preparing the solid states and processes for preparing Varenicline base from those Varenicline salts.

Solid state forms of varenicline salts and processes for preparation thereof

Crystalline forms of Varenicline Tosylate: are provided, along with processes for preparing those crystalline forms of Varenicline Tosylate, and processes for obtaining high purity Varenicline base using Varenicline Tosylate.

Varenicline tosylate, an intermediate in the preparation process of varenicline L-tartrate

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Rishon Lezion, Israel

Maytal Piran