Advanced Accelerator Applications Sa

Advanced Accelerator Applications (Italy) S.r.l.

Advanced Accelerator Applications

Advanced Accelerator Applications International Sa

Advanced Accelarator Applications International S.a.

Maurizio Mariani

Lorenza Fugazza

Daniela Chicco

Francesco De Palo

Donato Barbato

Giovanni Tesoriere

Clementina Brambati

Maria Azzurra Filannino

The present invention relates to radionuclide complex solutions of high concentration and of high chemical stability, that allows their use as drug product for diagnostic and/or therapeutic purposes. The stability of the drug product is achieved by at least one stabilizer against radiolytic degradation. The use of two stabilizers introduced during the manufacturing process at different stages was found to be of particular advantage.

Stable, concentrated radionuclide complex solutions

Chromatography columns for the purification of eluates fromGe/Ga generators comprising silica as stationary phase and purification processes that use said columns are described.

Process for the purification of Ga-68 from eluate deriving fromGe/Ga generators and chromatographic columns for use in said process

A process for the preparation of complexes containingGa wherein a buffer formic acid/formate in the presence of compounds capable to sequester metal cations is used in the complexation reaction.

[object Object]

A process for the preparation of complexes containingGa wherein a buffer formic acid/formate in the presence of compounds capable to sequester metal cations is used in the complexion reaction.

Growing community of inventors

Ivrea, Italy

Maurizio Mariani