Consiglio Nazionale Delle Ricerche

Universidade De Santiago De Compostela

Fidia Advanced Biopolymers S.r.l.

Fin-ceramica Faenza S.p.a.

Rejoint S.r.l.

Anika Therapeutics S.r.l.

Maurilio Marcacci

Lanfranco Callegaro

Anna Tampieri

Daniele Pressato

Monica Sandri

Elena Landi

Sergio Di Fede

José Rivas Rey

Manuel Banobre López

Manuel Banobre Lopez

The disclosure herein relates to various surgical methods for implanting a prosthesis in a patient. In particular, in some embodiments, a surgical method for preparing a knee of a patient to implant a customized knee prosthesis comprising: identifying epiphysary axis () of the patient tibia () by connecting the center of the tibial plateau with the center of the growth plate remnant on a preoperative planning; and performing a tibial cut () perpendicular to the epiphysary axis () of the tibia ().

Surgical method for implanting a prosthesis in a patient

The present invention relates to hydroxyapatite doped with Feions and Feions which partially substitute the calcium ions in the crystal lattice. The hydroxyapatite is characterized by an intrinsic magnetism of 0.05 to 8 emu/g, measured by applying a magnetic field of 34 Oe, due to the presence of magnetic nano-domains in the crystal lattice of HA, given the limited amount of magnetic secondary phases present, less than about 3% by volume. The intrinsically magnetic hydroxyapatite can be loaded with biological substances selected in the group consisting of proteins, genes, stem cells, growth factors, vascularization factors, active substances and drugs, under the control of an external magnetic field, as a carrier and release agent for biological substances or drugs, as a contrast agent in diagnostics or for bone or osteocartilage regeneration.

Intrinsically magnetic hydroxyapatite

The invention relates to use of a biological material containing cells supported on three-dimensional scaffolds containing at least one hyaluronic acid derivative for the preparation of grafts suitable for application by arthroscopy, and a kit of surgical instruments for implanting said biological material by arthroscopy.

Use of a biological material containing three-dimensional scaffolds of hyaluronic acid derivatives for the preparation of implants in arthroscopy and kit for instruments for implanting said biological material by arthroscopy

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Bologna, Italy

Maurilio Marcacci