Lubrizol Advanced Materials, Inc.

Mauricio Valerio Santiago

Consuelo García Hernández

Antonio Vicente Ferrer Montiel

Wim Van Den Nest

Albert Soley Astals

Núria Almiñana Doménech

Raquel Delgado Gonzalez

Núria Almiñana Domènech

Catalina Rodríguez Bielsa

A compound of formula (I) R-W-X-AA-AA-AA-AA-AA-AA-Y-Z-R, a stereoisomer and/or cosmetically acceptable salt thereof, and a method of treatment using the compound are described. In the compound, AAis Asp, Gly, Asn, Gln, Ala or no amino acid; AAis Val, Ile, Leu or Ala; AAis Tyr, Phe, Trp, Lys, Arg or His; AAis Lys, Arg, His, Pro or Val; AAis Asn, Asp, Gln or no amino acid; AAis Thr, Ala, Ser or no amino acid. The compounds are useful for the treatment of the symptoms of skin aging and, in particular, for the treatment of skin wrinkles, the treatment of a sagging appearance of the skin, and/or the reduction of facial asymmetry.

Compounds useful for the treatment and/or care of the skin, hair, nails and/or mucous membranes

A compound of formula (1) R—W—X-AA-AA-AA-AA-AA-AA-AA-AA-AA-Y—Z—R, wherein AAis Phe; AAis Trp; AAis selected from Met, Leu and lie; AAis selected from Lys, Arg and Gln; AAis Arg; AAis Lys; AAis selected from Arg, Lys and His; AAis selected from Val, Ile, Leu and Met; and AAis Pro. The compound is useful in the treatment and/or care of the skin, hair, nails and/or mucous membranes, in particular for improving the barrier function of the skin, for energizing the skin and as an anti-aging agent.

Growing community of inventors

Cadiz, Spain

Mauricio Valerio Santiago