Neumodx Molecular, Inc.

Akadeum Life Sciences, Inc.

Maureen Carey

Sundaresh N Brahmasandra

Elizabeth Craig

Michelle Mastronardi

Brandon H McNaughton

Casey Wegner

William Lloyd

Brittany MacIntyre

A system for partially or fully automated, buoyancy-assisted separation includes and/or interfaces with an automated instrument. Additionally or alternatively, the system can include and/or interface with any or all of: a set of buoyant particles, a set of containers (individually and/or collectively equivalently referred to herein as a consumable), a 1container management subsystem, a 2container management subsystem, a user interface subsystem, and/or any other components. A method for partially or fully automated, buoyancy-assisted separation includes manipulating the set of containers and/or processing the set of materials at a 1container management subsystem; and manipulating the set of containers and/or processing the set of materials at a 2container management subsystem.

Method and system for partially or fully automated buoyancy-assisted separation

A method for nucleic acid isolation comprising: receiving a binding moiety solution within a process chamber; mixing the binding moiety solution with a biological sample, within the process chamber, in order to produce a moiety-sample mixture; incubating the moiety-sample mixture during a time window, thereby producing a solution comprising a set of moiety-bound nucleic acid particles and a waste volume; separating the set of moiety-bound nucleic acid particles from the waste volume; washing the set of moiety-bound nucleic acid particles; and releasing a nucleic acid sample from the set of moiety-bound nucleic acid particles. The method preferably utilizes a binding moiety comprising at least one of poly(allylamine) and polypropylenimine tetramine dendrimer, both of which reversibly bind and unbind to nucleic acids based upon environmental pH.

Method and materials for isolation of nucleic acid materials

Growing community of inventors

Ann Arbor, MI, United States of America

Maureen Carey