Novartis Ag

Maude Nadine Pierrette Pipet

Nikolaus Johannes Stiefl

Catherine LeBlanc

Robert Alexander Pulz

Claire Adcock

Robin Alec Fairhurst

Urs Baettig

Peter Hunt

Duncan Shaw

Katrin Spiegel

Catherine Leblanc

Compounds of formula I in free or salt or solvate form, where T, T, X, R, R, Rand Rhave the meanings as indicated in the specification, are useful for treating inflammatory or obstructive airways, pulmonary hypertension, pulmonary fibrosis, liver fibrosis, muscle diseases and systemic skeletal disorders. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.

Organic compounds

Compounds of formula (I) in free or salt or solvate form, where T, T, Rand Rhave the meanings as indicated in the specification, are useful for treating inflammatory or obstructive airways, pulmonary hypertension, pulmonary fibrosis, liver fibrosis, muscle diseases and systemic skeletal disorders. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described. 

Pyrimidine derivatives as alk-5 inhibitors

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Horsham, United Kingdom

Maude Nadine Pierrette Pipet