Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt.

Matyas Szentivanyi

Sandor Virag

Antal Simay

Kalman Takacs

Ilona Kiss Nee Ajzert

Peter N Literati

Katalin Farago

Gabor Kovacs

Istvan Szekely

Gabor Bernath

Zoltan Ecsery

Judit Hermann Nee Voros

Lajos Gera

Erzsebet Janvari, Nee Kanyo

Gyorgy Gondos

A compound effective in the treatment of diabetic angiopathy, i.e. a selective .beta.-receptor blocker has the formula ##STR1## wherein: R.sup.2 is a hydrogen or alkyl having one to five carbon atoms,

O-(3-Amino-2-hydroxy-propyl)-amidoxime derivatives, process for the

N-Acylated 17-Aza-PGF.sub.2.alpha. compounds have been prepared.

Novel 17-aza-PGF.sub.2.alpha. derivatives and pharmaceutical

A compound effective in the treatment of diabetic angiopathy, i.e. a selective .beta.-receptor blocker has the formula ##STR1## wherein: R.sup.2 is a hydrogen or alkyl having one to five carbon atoms, R.sup.3 is alkyl having one to five carbon atoms, cycloalkyl or phenyl optionally substituted with hydroxyl or phenyl, or R.sup.2 and R.sup.3 together form a five- to eight-membered ring optionally containing also other heteroatoms and/or fused with an other ring, preferably phenyl, naphthyl, quinolyl, isoquinolyl, pyridyl, pyrazolyl, R.sup.5 is hydrogen or alkyl having one to four carbon atoms, cycloalkyl or phenyl optionally substituted with halogen, alkoxy having one to four carbon atoms or alkyl having one to four carbon atoms, R.sup.6 is hydrogen, alkyl having one to four carbon atoms or phenyl, m=0, 1 or 2, and n=0, 1 or 2.

New O-(3-amino-2-hydroxy-propyl)-amidoxime derivatives, process for the

An antiedema compound of the formula: ##STR1## in which R.sup.1 is methyl, ethyl, cyclohexyl, phenyl, m-tolyl, p-tolyl, p-tert-butylphenyl, m-trifluoromethylphenyl, m-fluorophenyl, p-fluorophenyl, m-chlorophenyl, p-chlorophenyl, m-bromophenyl, p-bromophenyl, o-hydroxyphenyl, p-methoxyphenyl, p-nitrophenyl, benzyl, p-chlorobenzyl, m,p-dimethoxybenzyl, and o-pyridyl;

5,6-Dihydropyrimidin-4(3H)one derivatives, and antiedema compositions

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Matyas Szentivanyi