Hasso-plattner Institut Fuer Softwaresystemtechnik Gmbh

Hasso-plattner-institut Fur Softwaresystemtechnik Gmbh

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Matthieu-Patrick Schapranow

Hasso Plattner

Emanuel Ziegler

Thomas Klein

Ralf Schliehe-Diecks

A system and a method for analyzing and evaluating genome data in the course of personalized medicine. In-memory technology is provided for processing of genome data and its real-time analysis as a holistic process in the course of personalized medicine. The cloud application helps physicians and researchers to identify the genetic roots for certain tumor types in the treatment of diseases correlating to genomic variants or mutations, such as cancer diseases. The system combines the latest international research results with patient-specific genomic data while eliminating the need for long-lasting manual searches of all dispositions in distributed international research and literature data sources.

System for genomic data processing with an in-memory database system and real-time analysis

The invention relates to system and a computer implemented method for use in the course of a clinical trial and/or precision medicine, wherein patient metrics are acquired and the system comprises selected core modules, methods and/or automated services and selected empowerment apps.

Immerse software-as-a-service patient empowerment platform for clinical trial participants

A high performance, low-cost, gapped read alignment algorithm is disclosed that produces high quality alignments of a complete human genome in a few minutes. Additionally, the algorithm is more than an order of magnitude faster than previous approaches using a low-cost workstation. The results are obtained via careful algorithm engineering of the seeding based approach. The use of non-hashed seeds in combination with techniques from search engine ranking achieves fast cache-efficient processing. The algorithm can also be efficiently parallelized. Integration into an in-memory database infrastructure (IMDB) leads to low overhead for data management and further analysis.

Efficient genomic read alignment in an in-memory database

The invention relates to a method for granting an inquirer querying a repository access to the repository, a communication protocol between a client and a server, and a system for controlling access of at least one inquirer to a repository. The repository typically stores event data relating to traceable products. The aspects according to teaching disclosed herein may be for example implemented as security extensions for existing repositories providing a finer granularity of access rights and means to prevent an exposure of data sets considered sensitive. The security extensions disclosed herein may be implemented to protect access to any kind of client/server application wherein the server is exposing sensitive data.

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Berlin, Germany

Matthieu-Patrick Schapranow