Diabetes Diagnostics, Inc.

Lifescan Corporation

Lifescan Scotland Limited

Inverness Medical Limited

Matthias Stiene

John J Allen

John M Allen

Patrick Mainville

Walter Francovich

Jerome F McAleer

Alan McNeilage

Piet H C Moerman

Tanja Richter

Manuel Alvarez-Icaza

James Iain Rodgers

James T Moffat

Elliot V Plotkin

Sebastian Bohm

Piet Moerman

Birgit Von Tiedemann

Lucy Macgregor

Jamie Roders

Jerry McAleer

Alan Mcneilage

Jerome Mcaleer

Jamie Rodgers

Jerry Mcaleer

Jerome F Mcaleer

Alun Griffith

Benoit Orban

Andreas Bode

Benjamin Coley

Gad Shaanan

An apparatus for detection and quantitation of an electrochemically-detectable analyte, such as glucose, in blood or interstitial fluid includes a meter unit, a lancet and an electrochemical sensor. Of these components, the meter is preferably reusable, while the lancet and the electrochemical sensor are preferably incorporated in assemblies intended for single-use. The meter unit has a housing, within which a lancet is engaged with a mechanism for moving then lancet; a connector disposed within the housing for engaging an electrochemical sensor specific for the analyte and transmitting a signal indicative of the amount of analyte, and a display operatively-associated with a connector for displaying the amount of the analyte to user. The electrochemical sensor is adapted for detection of a particular analyte. In addition, the electrochemical sensor has an absorptive member for uptake of a sample of blood or interstitial fluid. In one version, the lancet moves from a initial position to a piercing position in which skin of the user is pierced and optionally back to a retracted position. The electrochemical sensor is disposed such that the absorptive member takes up a sample from the pierced skin of the user when it is pierced by the lancet without movement of the apparatus. In an alternative version, the lancet is a hollow cannula through which blood or interstitial fluid is transported from the puncture site to an absorbent portion of the electrochemical sensor. In either version, the apparatus provides single-step operation in which sample acquisition and analysis occur as a result of the single action of pressing the apparatus against the users skin.

Combined lancet and electrochemical analyte-testing apparatus

A device and method for measuring clotting times in a fluid, typically blood, within a microchannel, with the onset of clotting being determined by measurement of the rate of change, or the value, of capacitance or impedance between two electrodes situated on either side of the microchannel. The device includes an upper support member and a lower support member with a microchannel formed therein. The device also includes electrodes situated along the length of the microchannel.

Device for measuring blood coagulation and method thereof

A microfluidic analytical system for monitoring an analyte (for example, glucose) in a liquid sample (e.g., ISF) includes an analysis module with at least one micro-channel for receiving and transporting a liquid sample, at least one analyte sensor for measuring an analyte in the liquid sample and at least one position electrode. The analyte sensor(s) and position electrode(s) are in operative communication with the micro-channel. The microfluidic system also includes a meter configured for measuring an electrical characteristic (such as impedance or resistance) of the position electrode(s). Moreover, the measured electrical characteristic is dependent on the position of the liquid sample in the micro-channel that is in operative communication with the position electrode for which an electrical characteristic is measured.

Microfluidic analytical system with position electrodes

The invention relates to a paste, which can undergo screen printing, for producing a porous polymer membrane. Said paste contains at least one polymer, one or more solvents for the polymer having a boiling point of >100&deg; C., one or more non-solvents for the polymers (pore-forming agents) having a higher boiling point than that of the solvent(s), and contains a hydrophilic viscosity modifier.

Paste, which can undergo screen printing for producing a porous polymer membrane for a biosensor

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Inverness, United Kingdom

Matthias Stiene