Sanofi-a Ventis Deutschland Gmbh

Hoechst Aktiengesellschaft

Matthias Scharf

Jan-Peter Spengler

Jasmin Groeschke

Michael Schrack

Hanno Juhnke

Olaf Zeckai

Christoph Dette

Hardy Kietzmann

Alexander Allerdings

Andreas Bode

Michael Fischer

Paul Habermann

Dominique Tripier

Peter Crause

Joachim Engels

Jurgen Hemberger

Martin Kramer

Jürgen Hemberger

Anne Boker

Michael Scharack

Anne BÖKER

An apparatus is disclosed, comprising a detector unit comprising a detector configured to detect an actuation action performable via the detector unit to an actuation button of a medical device to cause the medical device to eject at least a portion of a medicament comprised in the medical device. The detector is configured to detect the actuation action based on a detection of a force and/or a touch applied to the detector unit as part of the actuation action. The apparatus further comprises an electric unit connected to the detector and configured to store and/or provide information related to the detected actuation action. Furthermore, an according method and a computer program for controlling this method are disclosed.

Device and method for detecting an actuation action performable with a medical device

The present invention relates to a drive mechanism for a drug delivery device, comprising: a piston rod to operably engage with a piston of a cartridge to displace the piston in a distal direction during a dose dispensing action, at least one actuation member mechanically coupled with the piston rod to induce a distally directed displacement of the piston rod when actuated by a user, a control to ascertain at least one predefined condition of use, and at least one interlock member coupled with the control to mechanically obstruct displacement of the piston rod if the condition of use is not fulfilled.

Pen-type drug injection device with controller and time lock-out mechanism for its drive

The present invention relates to a method of testing the mechanical integrity of a cartridge () containing a medicament and being arranged inside a drug delivery device (). The invention also relates to a testing arrangement and to a respective drug delivery device, wherein the method comprises the steps of: acoustically stimulating the cartridge (), measuring of the cartridge's () acoustic response () to the acoustic stimulation (), comparing the acoustic response () with a standard response () of an intact cartridge (), and determining the mechanical integrity of the cartridge () on the basis of the comparison.

Method and arrangement for acoustically testing the mechanical integrity of a cartridge

The present invention relates to a monitoring device for monitoring operation of a drug delivery device and to a respective drug delivery device, wherein the monitoring device comprises:

Monitoring device for monitoring operation of a drug delivery device

A testing device for testing the mechanical integrity of a hollow breakable item includes a squeezable element to radially abut with a sidewall portion of the breakable item. The testing device further includes a sleeve extending in an axial direction to receive the sidewall portion of the breakable item and having a first contact surface to axially engage with the squeezable element. The testing device also includes a plunger displaceable in axial direction relative to the sleeve and having a second contact surface to axially engage with the squeezable element. The squeezable element is axially squeezable by a relative displacement of plunger and sleeve to increase the squeezable element's radial expansion and to apply radially directed pressure to the breakable item's sidewall portion.

Device and method for testing the mechanical integrity of cartridges for liquid medicaments

The present invention relates to a drug delivery device for dispensing a dose of a medicament, comprising: a first housing component, and a second housing component welded with the first housing component by at least one induction heatable component.

Welded housing components of a drug delivery device

The present invention relates to an assembly line to assemble a medical device and comprising at least one communication member adapted to communicate with a corresponding communication member of an initial component of the device, wherein the assembly line comprises at least one assembly stage adapted to conduct at least one step of assembly being at least influenced by device-related data obtained from the component.

Component of a drug delivery device and method of assembly

A monitoring device for monitoring operation of a drug delivery device and to a respective drug delivery device is presented in which a fastening member releasably attaches the monitoring device to an axially elongated housing of the drug delivery device, a sliding member is shiftable relative to the fastening member in an axial direction and being adapted to operably engage with at least one dose setting component of the drug delivery device to follow an axial displacement of the dose setting component relative to the housing component, a first sensor arrangement for detecting a rotation of the dose setting component relative to the fastening member, a second sensor arrangement for detecting an axial displacement of the sliding member relative to the fastening member, and a processing member coupled to the first and to the second sensor arrangements to process first and second signals obtainable from the first and from the second sensor arrangements for determining the size of a dose dispensed by the drug delivery device.

Pen-type drug injection device and electronic add-on monitoring module for monitoring and logging dose setting and administration

Thrombin inhibitors from the hirudin family which differ from the previously known hirudins by mutation in the protein chain, and a process for their preparation are described. The novel hirudins are distinguished by a high specific activity, high stability and good pharmacokinetics.

Growing community of inventors

Frankfurt am Main, Germany

Matthias Scharf