Evonik Degussa Gmbh

Evonik Industries Ag

Hte Aktiengesellschaft the High Throughput Experimentation Company

Matthias Orschel

Gerda Grund

Axel Hengstermann

Robert Jansen

Joerg-Joachim Nitz

Christian Lettmann

Guido Streukens

Markus Schwarz

Martin Maier

Stephan Kohlstruk

Peter Duerre

Hubert Johannes Bahl

Matthias Mendorf

Steffen Schaffer

Armin Matthias Rix

Martina Ortelt

Gerd Loehden

Friedrich Georg Schmidt

Ralf-Joerg Fischer

Antje May

Anne Rittsteiger

Alexander Martin Rüfer

Stefan Verseck

Jörg-Joachim Nitz

Jens Klein

Werner Freitag

Michael Demming

Franz Ulrich Becker

Cord Knoop

Kai Doderer

Jens Doering

Wilhelm F Maier

Anja Mueller

Andreas Merkel

Jens Döring

Markus Galle

Anja Müller

Juergen Lippe

Ulrich Becker

Norbert Richter

Hans Werner Schmidt

Gerd Löhden

Simone Lederle

Wilfried Schmidt

Friedrich-Georg Schmidt

Andreas Hoff

Jorn Walscharts

Rolf Hirsch

Michael D Hinton

Simone Thum

Peter Dürre

Gerd Brand

Ralf-Jörg Fischer

A process for fine purification of isophoronediamine (IPDA), including producing IPDA by aminating hydrogenation of isophorone nitrile in the presence of at least ammonia, hydrogen, a a hydrogenation catalyst and optionally further additions to obtain a crude IPDA, and subjecting the crude IPDA to a fine purification via two vacuum distillation columns, wherein in the first vacuum distillation column the removal of any remaining relatively low-boiling byproducts is effected and in the second vacuum distillation column the IPDA is obtained in pure form as tops and thus separated from the organic residues, and wherein the first vacuum distillation column has vacuum distillation column has a partial condenser fitted to it.

Coupling of distillative purification with a partial condenser for pre-purification of isophoronediamine

The invention relates to cells and a method for producing acetone.

Cells and method for producing acetone

The invention relates to an improved process for preparing 3-aminomethyl-3,5,5-trimethylcyclohexylamine, referred to hereinafter as isophoronediamine or, in abbreviated form, IPDA, by: I. preparation of isophorone by catalyzed aldol condensations with acetone as reactant; II. reaction of isophorone with HCN to form isophoronenitrile (IPN, 3-cyano-3,5,5-trimethylcyclohexanone); III. catalytic hydrogenation and/or catalytic reductive amination (also referred to as aminative hydrogenation) of 3-cyano-3,5,5-trimethylcyclohexanone, hereinafter called isophoronenitrile or, in abbreviated form, IPN, to give the isophoronediamine.

Process for preparing 3-aminomethyl-3,5,5-trimethylcyclohexylamine

A process for preparing isophorone (3,5,5-trimethyl-2-cyclohexen-1-one) is provided wherein distillation vapors from the work-up of product fractions are recycled to earlier stages of operation of the process.

Hydrolysis of the residues obtained in the production of isophorone to recover isophorone and acetone

The invention describes a process for preparing acetone starting from acetyl-coenzyme A comprising process steps A. enzymatic conversion of acetyl-CoA into acetoacetyl-CoA B. enzymatic conversion of acetoacetyl-CoA into acetoacetate and CoA and C. decarboxylation of acetoacetate to acetone and CO, which is characterized in that the coenzyme A is not transferred in process step B to an acceptor molecule. In addition, process step B is surprisingly catalyzed by enzymes of the classes of acyl-CoA thioesterase, acyl-CoA synthetase or acyl-CoA thiokinase. A completely novel metabolic pathway is concerned, because the enzymatic hydrolysis of acetoacetyl-CoA without simultaneous transfer of CoA to a receptor molecule has never previously been described for any microbial enzyme.

Fermentative production of acetone from renewable resources by means of novel metabolic pathway

The invention relates to a method for producing isophorone by catalyzed aldol condensation of acetone as an educt, reprocessing the reaction product, hydrolyzing the product stream, and separating into an organic and an aqueous fraction, obtaining isophorone from the organic fraction, distillatively reprocessing the aqueous fraction, and feeding the vapors from the head of the distillative reprocessing apparatus into the hydrolysis apparatus.

Method for producing isophorone

The invention relates to a process for preparing isophorone (3,5,5-trimethyl-2-cyclohexen-1-one) in the presence of at least one defoamer in the wastewater column in the workup section.

Process for preparing isophorone in the presence of at least one defoamer in the wastewater column in the workup section

The invention relates to an improved process for preparing 3-aminomethyl-3,5,5-trimethylcyclohexylamine, referred to hereinafter as isophoronediamine or IPDA for short, by means of catalytic hydrogenation and/or catalytic reductive amination (also referred to as aminating hydrogenation) of 3-cyano-3,5,5-trimethylcyclohexanone, also called isophoronenitrile or IPN for short hereinafter.

The invention relates to an automated method for carrying out reactions with high spatial resolution on libraries of different materials and for analysis of the products obtained using a simple robot system and an analyzer, for example a mass spectrometer.

Automated method for examining catalytic and spectroscopic properties of the components of combinatorial libraries

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Muenster, Germany

Matthias Orschel