Merck Sharp + Dohme Corp.

Matthew Walker, Iii

Craig Fancourt

Karim Azer

The present invention uses a microprocessor, a memory storage device, and a segmentation program comprising a plurality of program modules containing computer-readable instructions that cause the microprocessor to measure the spatial offsets between all pairs of scans in an m-mode image of a blood vessel with a cross-correlation function, convert the spatial offsets to a relative wall motion waveform through a global optimization procedure, and then translate the relative wall motion waveform to an absolute wall motion waveform by interpolation over the m-mode image. The resulting detailed absolute wall distension waveform may be beneficially rendered (e.g., superimposed) on the m-mode ultrasound image for display (e.g., on a printer and/or video monitor) and diagnostic purposes, and has enormous potential for enhancing existing techniques for identifying and studying vascular biomarkers, such as vessel wall strain and compliance.

Growing community of inventors

New York, NY, United States of America

Matthew Walker, Iii