The Texas A&m University System

Szafron, Jason M.

Muschenborn, Andrea D.

Wierzbicki, Mark A.

Nash, Landon

Maitland, Duncan

Landsman, Todd

Miller, Matthew W.

Matthew W Miller

Duncan J Maitland

Landon D Nash

Todd L Landsman

Mark A Wierzbicki

Andrea D Muschenborn

Jason Szafron

James C Sacchettini

Nian E Zhou

Deeann Wallis

Theresa W Fossum

Jason M Szafron

Todd Landsman

Duncan Maitland

Landon Nash

A device for a tissue channel includes a device frame, a shape memory polymer foam segment coupled to the device frame, and an attachment structure coupled to the device frame. The device frame includes a proximal structure, a distal structure, and an intermediate structure coupled to the proximal structure and the distal structure. The proximal structure is configured to collapse to fit into a delivery structure and expand to block migration of the proximal structure. The distal structure is configured to collapse to fit into the delivery structure and expand to block migration of the distal structure. The intermediate structure is configured to fit in the tissue channel upon device deployment. The shape memory polymer foam segment is configured to compress to fit into the delivery structure and occlude the channel. The attachment structure is configured to attach and detach the device from a delivery guide.

Biocompatible biomedical occlusion device

Compositions and methods for inhibiting and/or sensitizing or re-sensitizing a parasite to an antiparasitic drug are provided. The compositions can comprise a rifamycin derivative or a pharmaceutically acceptable salt, hydrate, or prodrug thereof in an amount and formulation sufficient to inhibit or induce drug-sensitization in a parasite. The methods can comprise administering a rifamycin derivative or a pharmaceutically acceptable salt, hydrate, or prodrug thereof to a parasite in an amount and formulation sufficient to inhibit or induce drug-sensitization in the parasite.

Compositions and methods for drug sensitization of parasites

Growing community of inventors

Carefree, AZ, United States of America

Matthew W Miller