Sky High, LLC

Lxr Biotechnology, Inc.

Matthew W Foehr

Ian C Bathurst

John D Bradley

Donald H Picker

J Graham Goddard

Samiul R Umansky

Philip J Barr

L David Tomei

John G Goddard

Winston Wicomb

Geoffrey Collins

The present invention provides therapeutic compositions containing lysophosphatidic acids, methods for making the compositions, and methods of use thereof.

Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof

The present invention provides methods for extracting anti-apoptotic compositions from various protein isolates and/or lipid mixtures with aqueous solutions not containing organic solvents. The compositions extracted by the methods can be used for a variety of purposes, including for therapeutic, nutritional and medicinal purposes.

Aqueous anti-apoptotic compositions

The present invention provides therapeutic compositions containing lysophosphotidic acids, methods for making the compositions, and methods of using the compositions in the preservation and treatment of organs.

A composition comprising a storage-stable organ preservation solution, comprising a linear polyethylene glycol having an average molecular weight of approximately 20,000 Daltons and being essentially free of decomposition products. This solution can be used for organ preservation as a perfusate in a process in which the perfusate is flowed through the circulatory system of the organ, and can also be used for transplantation or routine open heart cardioplegic applications. The composition can be contained in a system comprising a means for preventing light exposure, especially UV light, to the solution. In addition, the system is preferably impervious to gases, particularly oxygen.

System for storing polyethylene glycol solutions

Compositions which inhibit apoptosis, methods of making the compositions

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San Francisco, CA, United States of America

Matthew W Foehr