3m Innovative Properties Company

Minnesota Mining and Manufacturing Company

Other

University of Minnesota

Riker Laboratories Inc.

Solventum Intellectual Properties Company

Matthew T Scholz

Robert A Asmus

Ranjani V Parthasarathy

Dean A Ersfeld

Caroline M Ylitalo

Robert A Scherrer

Kevin D Landgrebe

Timothy C Sandvig

Nicholas R Baumann

Michael R Berrigan

Dong-Wei Zhu

Jay M Jennen

Mahfuza B Ali

Robin Edgar Wright

John D Stelter

Eric M Moore

Raymond Patrick Johnston

Steven B Heinecke

Kevin R Schaffer

Gilbert L Eian

Steven P Swanson

Kent E Lageson

Audrey A Sherman

Thomas P Klun

Ramesh C Kumar

George V Tiers

Dennis G Welygan

William L Kausch

Louis C Haddad

Richard S Buckanin

F Andrew Ubel

Yifan Zhang

Michael Alan Meis

Stephen C P Joseph

Wayne K Dunshee

Timothy J Hebrink

Kurt J Halverson

Steven S Kantner

Amanda Catherine Engler

Dale P DeVore

Scott A Burton

Scott J Tuman

Diane R Wolk

Stephen P Maki

Kenneth A Peterson

Michael D Delmore

Alan R Dombrowski

Wayne K Larson

Nicholas Ransom Powley

David R Boston

Douglas A Hanggi

Naiyong Jing

Jerald K Rasmussen

Joel D Oxman

Kevin Michael Lewandowski

George W Griesgraber

David B Olson

Stephen A Johnson

Chetan P Jariwala

William Bedingham

Ronald Wayne Ausen

Thomas Edward Wood

Andrew R Fox

Richard G Hansen

Jeffrey O Emslander

Kannan Seshadri

Scott D Pearson

Christopher Bland Walker, Jr

David S Hays

Stephen M Sanocki

Jon A Kirschhoffer

Nicolas A Echeverri

Naimul Karim

Paul E Hansen

David R Holm

Alphonsus V Pocius

Albert Philip Van Duren

John J Stofko, Jr

Charles David Hoyle

Hatim M Carim

Caleb T Nelson

John M Brandner

Zhiming Zhou

Andrew Jacob McGregor

Terry R Hobbs

Gregg A Patnode

Thu-Van T Tran

Timothy J Lindquist

Thomas J Packard

Pradnya V Nagarkar

Marie A Boulos

Joon Chatterjee

Terence D Neavin

Ranjith Divigalpitiya

Zhiqun Zhang

Raymond D Skwierczynski

Kurt C Melancon

Daniel W Davis

Donald R Battles

Bradley W Eaton

The disclosed antiseptic composition has improved stability, flow control and tinting ability is provided. The antiseptic composition comprises a cationic antiseptic, an anionic tinting agent, a polymer that serves as a stabilizer and preferably a viscosity builder, an alcohol-based solvent and optionally a plasticizer and viscosity builder.

Antiseptic skin prep composition

Compositions including a quaternary amine antiseptic component having a concentration of at least about 0.04% by weight; a poly carboxylic acid chelator having a concentration of at least about 0.05 M and/or an alphahydroxy acid buffer having a concentration of at least about 0.05 M; a (C8-C12) 1,2 alkane diol; and optionally water are provided. The compositions have a pH greater than or equal to 3.5 and less than 5.5 at 23° C. In certain embodiments, water is present in the composition at a greater weight percent than each of the quaternary amine antiseptic component; the polycarboxylic acid chelator, if present; the alphahydroxy acid buffer, if present; and the (C8-C12) 1,2-alkane diol. In certain embodiments, water is present in the composition at a greater weight percent than any other component.

Antimicrobial compositions with 1,2-alkanediols

A product authentication system includes one or more image capture devices that provide video data representative of an enhanced safety environment. The product authentication system can determine the continuous presence of a designated product during a time period, for example, during performance of a task in an enhanced safety environment. The video data can be spatiotemporally sliced according to multiple orientations with respect to the time axis and the two spatial axes. A plurality of data streams are created where the slices of each respective data stream have the same orientation. The data streams are processed according to one or more machine learning models, such as convolutional neural networks trained to determine whether the designated product is continuously present in the video data. An indicator of the continuous presence of the designated product can be provided to a downstream system and used to indicate whether functions of the downstream system are to be performed.

Video based continuous product detection

Multilayer optical film comprising at least a plurality of alternating first and second optical layers. Embodiments of the multilayer optical film are useful, for example, in UV-C shield, UV-C light collimator, and UV-C light concentrator applications.

Multilayer optical films and articles comprising the same

A light guide comprising a polymeric layer at least 25 percent transmissive over at least a 30 nm bandwidth in a wavelength range from 180 to 280 nm over a distance of at least 100 micrometers and visible light transparent reflecting layers (UV-C mirror) that are at least 50 percent reflective over at least 30 nm bandwidth in a wavelength range from 180 to 280 nm over an incident light angle of 0 to 90 degrees and that are at least 25 percent transmissive of visible light over at least 30 nm bandwidth in a wavelength range of 400 to 800 nm over an incident light angle of 0 to 90 degrees. The light guide is useful, for example, for antimicrobial surfaces.

Ultraviolet C light guides

Disclosed herein are methods that include contacting a skin surface with a first liquid composition; and then contacting in the skin surface with a cationic coated article loaded with a second liquid composition, while at least some portion of the first liquid composition remains on the skin surface, wherein one or both of the first liquid composition or the second liquid composition includes acrylate copolymer particles dispersed therein, the acrylate copolymer particles including the reaction product of a reaction mixture, the reaction mixture including monomers, the monomers including from about 5 wt % to about 50 wt % of at least one high Tg monomer where the wt % of the high Tg monomer is with respect to the total weight of the monomers in the reaction mixture; and from about 20 wt % to about 80 wt % of at least one low Tg monomer where the wt % of the low Tg monomer is with respect to the total weight of the monomers in the reaction mixture, wherein the particles have a number average diameter of at least about 100 nm and wherein at least one and only one of the first or the second composition comprises greater than or equal to 60 wt % of at least one alcohol.

Methods of removing spores comprising alcohol, acrylate copolymer particles, and a cationic coated article

Aspects of the present disclosure relate to a warming system. The warming system includes a light device having a light source configured to be positioned proximate to a patient support having a patient support surface. The light source can also be configured to generate infrared radiation. The warming system can also include a flexible sheet having a first side configured to reflect at least some of the generated infrared radiation from the light device toward a portion of the patient support surface.

Radiative warming system

A copolymer composition that includes a silicone copolymer, methods of making the composition, and articles that include the composition, wherein the copolymer composition includes a silicone copolymer having a backbone composition that includes: silicone segments in an amount of 5 wt-% to 40 wt-%, based on the total weight of the silicone copolymer; hydrophilic segments in an amount of 40 wt-% to 75 wt-%, based on the total weight of the silicone copolymer; and reinforcing segments in an amount of 5 wt-% to 30 wt-%, based on the total weight of the silicone copolymer, wherein the reinforcing segments are derived from the reaction of one or more chain extenders with one or more multi-functional isocyanates, multi-functional carboxylic acids, multi-functional anhydrides, multi-functional esters, and/or multi-functional acid halides; wherein the silicone segments, hydrophilic segments, and reinforcing segments are connected through urea, urethane, amide, and/or oxamide linkages; wherein the hydrophilic segments and the reinforcing segments are present in a weight ratio of 1.8:1 to 8:1; and the hydrophilic segments and the silicone segments are present in a weight ratio of 1.3:1 to 4.5:1.

Silicone copolymers, methods of making, and articles

A system and methods for sterilizing or disinfecting articles, particularly the hollow internal areas of medical instruments are disclosed. The system includes a plasma generator having an electrode, a shield, and a dielectric gap between the electrode and the shield. A source of electrical power is connected to the plasma generator for applying an electron energy density between the electrode and the shield. A source of gas comprising water vapor, oxygen and nitrogen provides a flow of gas between the electrode and the shield, to form a plasma containing acidic and/or oxidizing species. In the exemplary system, the temperature at the shield's surface is &#x3c;150&#xb0; C. when the electron energy density is &#x3e;0.05 eV/molecule of the gas. Also disclosed is a method for disinfecting an article contaminated with a bio-film or spores, by exposing the contaminated article to the plasma for an exposure time sufficient to achieve at least 2-logreduction in colony forming units.

Plasma sterilization system and methods

Methods of delaying the onset of an infection or preventing an infection caused by a microbial organism in an internal cavity of a subject are provided. Methods of killing or inactivating microorganisms in at least a portion of the urethra of a subject are provided.

Methods of reducing microbial contamination

Multilayered polymer films are configured so that successive constituent layer packets can be delaminated in continuous sheet form from the remaining film. The films are compatible with known coextrusion manufacturing techniques, and can be made without adhesive layers between layer packets that are tailored to be individually peelable from the remainder of the film. Instead, combinations of polymer compositions are used to allow non-adhesive polymer layers to be combined such that irreversible delamination of the film is likely to occur at interfaces between layer packets pairs. Some of the polymer layers, including at least one embedded layer, comprise an antimicrobial agent, and these layers may be positioned at the front of each layer packet. After the antimicrobial layer of one layer packet has been used, the packet can be peeled away to expose a pristine antimicrobial layer of the next layer packet. The antimicrobial agent may be organic.

Successively peelable coextruded polymer film with embedded antimicrobial layer(s)

A composite wound dressing apparatus promotes healing of a wound via the use of a micropump system. The micropump system includes a micropump that applies a subatmospheric pressure to the wound to effectively draw wound fluid or exudate away from the wound bed, or deliver fluids to the wound bed, without the need for a cumbersome external pressure (e.g. vacuum) source. Hence, the wound dressing and micropump system is portable which allows the patient mobility that is unavailable when an external vacuum source is used.

Wound dressing with micropump

Shapeable articles, kits including one or more of the shapeable articles, and methods of making and/or using the shapeable articles. The shapeable articles include a shapeable member that can be shaped or manipulated into three-dimensional shapes without the use of tools and hold those shapes after removal of the force required to achieve the shape. The shapeable articles could have a variety of uses including use as surgical retractors to move and/or restrain non-target tissue and/or organs to improve access to the target tissue and/or organs.

Shapeable articles and methods of making and using the same

The present disclosure describes articles, such as medical articles, containing a substrate having disposed thereon a hydrophilic gel material (e.g., a shaped hydrophilic gel material or a coating of a hydrophilic gel material) and methods for making such articles. Methods are provided for making hydrophilic gel materials from a precursor composition that contains a polar solvent and a polymerizable material that is miscible with the polar solvent.

Hydrophilic gel materials and methods of making

Disclosed herein are compositions that include at least about 85 wt % of a hydroalcoholic solution that includes at least about 1 wt % water; and about 30 to about 85 wt % of at least one C1 to C4 alkyl alcohol based on the total weight of the hydroalcoholic solution; and acrylate copolymer particles dispersed in the hydroalcoholic solution, the acrylate copolymers particles being the reaction product of a reaction mixture, the reaction mixture including monomers, the monomers including from about 5 wt % to about 50 wt % of at least one high Tg monomer; and from about 20 w % to about 80 wt % of at least one low Tg monomer where the wt % of the low and high Tg monomers are with respect to the total weight of the monomers in the reaction mixture, wherein the particles have a number average diameter of at least about 100 nm.

Compositions for spore removal

Growing community of inventors

Woodbury, MN, United States of America

Matthew T Scholz