Monsanto Technology LLC

Duke University

Matthew Sean Marengo

Edward James Cargill

Ty Jason Barten

Romain Fouquet

Dennis Hung Yang

Jose Rafael Gomez

Manuel Oyervides Garcia

Jeanette M Peevers

Alana N Brown

Mariano A Garcia-Blanco

Catherine Alice Chay

David Joseph Bowen

Arlene R Howe

Jason S Milligan

Jonathan C Lamb

Brent A O'Brien

Brian E Weiner

Jason Meyer

Matthew J Bauer

Lisa Kanizay

The present disclosure is in the field of plant breeding. The disclosure provides methods for breeding corn plants having a brachytic trait using marker-assisted selection. The disclosure further provides brachytic germplasm, markers associated with a brachytic trait for introgressing the trait into elite germplasm in a breeding program. This disclosure also provides brachytic or dwarf elite corn varieties having yield equal to or higher than conventional non-brachytic corn varieties.

Methods and compositions for producing brachytic corn plants

This disclosure provides methods and compositions for increasing genome editing and site-directed integration events utilizing guided endonucleases and meiotic cell-preferred, egg cell-preferred or embryo tissue-preferred promoters.

Increasing gene editing and site-directed integration events utilizing meiotic and germline promoters

Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC4029, TIC4029_1, and TIC4029_8. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding pesticidal proteins of the TIC4029 class. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the TIC4029 class in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC4029, TIC4029_1, and TIC4029_8 pesticidal proteins are also provided.

Insect inhibitory proteins

Synthetic regulation of gene expression is provided. In some embodiments, synthetic regulatory constructs are provided. In some embodiments, a synthetic regulatory construct expresses a heterologous gene in a selected cell type. In some embodiments, methods of expressing a heterologous gene in a selected cell type are provided.

Synthetic regulation of gene expression

Growing community of inventors

Cary, NC, United States of America

Matthew Sean Marengo