Becton Dickinson and Company Limited

Pearl Therapeutics, Inc.

Dunan Microstaq, Inc.

Other

Matthew S Ferriter

Vincent J Sullivan

P Spencer Kinsey

John M Polidoro

Carl R Sahi

Kenneth G Powell

Ge Jiang

Jill Sherwood

Ronald J Pettis

Michael Thomas Riebe

Fred Hamlin

Parthiban Arunasalam

Michael L King

Frank E Martin

Joe Albert Ojeda, Sr

E Nelson Fuller

Scott Nicholas Danhof

Sarvajna Kumar Dwivedi

Richard Klug

Wayne Curtis Long

Eric Hassenpflug

Steven Keith

John A Mikszta

George McGee Perkins

Joshua Herr

Christopher Rini

Joseph Nguyen

Anjana Bhuta Wills

John P Dekker, Iii

Natasha Bolick

Wendy Dale Woodley

Michael Leon Franklin

Frances Poyen Tong

Alfred Joseph Harvey

Elaine McVey

Robert V Sheehy, Jr

Denny Himel

Brian Foster

Dan Deaton

C Robin Hwang

Daniel Deaton

Daniel Marion Deaton, Iii

Mircea Stefan Despa

Scott Alexander Lewis

Adam Martin

Ralph Lamble

John Kenneth Hainsworth

Jill K Sherwood

Spencer P Kinsey

Scott Lewis

John Hainsworth

Richard J Klug

John P Iii Dekker

Elaine Mcvey

Fred William Hamlin

Jill Karen Sherwood

Vince J Sullivan

Alfed Joseph Harvey

Elaine Mc Vey

Frances Tong

Kyle Woodard

Robert V Sheehy

Eric G Hassenpflug

Gerard Libby

Vipul Negi

A valve for permitting mixing of at least two components within a barrel is provided including a stopper configured for slidable liquid-tight engagement with an inner surface of the barrel. The stopper is moveable between a first position and a second position and includes a proximal end, a distal end, and a channel extending therebetween. The valve further includes a stationary body comprising a base and a stem, the stem being disposed within the channel of the stopper when the stopper is in the second position. When the stopper is in the first position, there is a liquid-tight seal in the channel, such that fluid flow through the channel is prevented. Movement of the stopper to the second position terminates the liquid-tight seal, thereby establishing fluid communication through the channel. A drug containing device and assembly for delivering a reconstituted drug are also provided herein.

Valve permitting mixing in a drug delivery device

There is provided an electronically controlled, motor-driven, breath actuated metered dose inhaler for delivering aerosolized medicament or other matter to a user. The inhaler may comprise a base housing including a motor-driven actuator and other system components and a removable aerosol cartridge insertably receivable in the base housing. The inhaler may be paired with a smart phone or other client computing device to provide additional functionality, such as to provide instructional information and feedback regarding usage of the inhaler, to generate and display dosage tracking information, and to provide alerts and reminders to a user of the inhaler or others.

Aerosol delivery systems and related methods

Systems and methods for isolating and/or desiccating a portion of a drug delivery tract of a drug delivery apparatus to reduce water vapor content therein are provided. For example, there is provided a metered dose inhaler for delivering aerosolized medicament or other matter to a user. The aerosolized medicament or other matter may be discharged from a discharge passageway within the inhaler into an inhalation passageway for inhalation by a user, and the inhaler may comprise a seal member operative to selectively isolate the discharge passageway from the inhalation passageway and external environment during inactivity. The inhaler may further comprise a desiccant material arranged to withdraw moisture from the isolated discharge passageway. In other instances, desiccant material may be arranged to withdraw moisture from the discharge passageway of the inhaler without isolating the discharge passage during inactivity.

Drug delivery systems and related methods

A controlled delivery syringe device includes a syringe barrel having a proximal end and distal end which defines a chamber for containing an injectable material. A plunger rod is associated with the syringe barrel and a plunger is secured thereto which is axially movable within the syringe barrel. A plurality of equally and sequentially spaced periodic features are associated with the plunger rod and a counter member is engageable with the periodic features. Application of a distally directed force to the plunger rod results in disengagement and reengagement of the counter member with the sequentially spaced periodic features on the plunger rod, enabling advancement of the plunger rod and plunger in the syringe barrel while providing tactile feedback of dose progression of the injectable material. A method of retrofitting a syringe with a device for injecting a metered dose of injectable material is also provided.

Controlled delivery syringe device

Aerosol delivery systems

An improved aerosol dispensing apparatus includes an aerosol container, a discharge piece movably mounted to the aerosol container, a flow control valve mounted within the discharge piece, a battery, and an electronically controlled metering valve electronically connected to the battery and in fluid communication with the flow control valve. The flow control valve is movable between an open position wherein a volume of an aerosol formulation is directed from the aerosol container through the flow control valve to the metering valve, and a closed position, wherein the metering valve is configured to precisely control a flow of the aerosol formulation outward of the discharge piece. A solenoid is electronically connected to the battery and is movable between an actuated position wherein the solenoid urges the flow control valve into the open position, and an un-actuated position wherein the flow control valve remains in the closed position.

Metering valve for a metered dose inhaler

An improved aerosol dispensing apparatus includes an aerosol container, a discharge piece movably mounted to the aerosol container, a metering valve mounted within the discharge piece, a battery, and an electronically controlled flow control valve. The flow control valve is electronically connected to the battery and is in fluid communication with the metering valve. The metering valve is movable between an open position wherein a volume of an aerosol formulation is directed from the aerosol container through the metering valve to the electronically controlled flow control valve, and a closed position wherein the aerosol formulation is not permitted to flow through the metering valve. The electronically controlled flow control valve is configured to precisely control a flow of the aerosol formulation outward of the discharge piece.

A valve () for permitting mixing of at least two components within a barrel () is provided including a stopper () configured for slidable liquid-tight engagement with an inner surface () of the barrel. The stopper is moveable between a first position and a second position and includes a proximal end (), a distal end (), and a channel () extending therebetween. The valve further includes a stationary body () comprising a base () and a stem (), the stem being disposed within the channel of the stopper when the stopper is in the second position. When the stopper is in the first position, there is a liquid-tight seal in the channel, such that fluid flow through the channel is prevented. Movement of the stopper to the second position terminates the liquid-tight seal, thereby establishing fluid communication through the channel. A drug containing device and assembly for delivering a reconstituted drug are also provided herein.

A system and method for a patch-like, self-contained multi-component substance infusion device which provides one or more substantially hidden patient needles which can be placed in fluid communication with a fluid reservoir assembly that includes a rigid bladder portion used in conjunction with a non-distensible bladder film, such as a metallized film. The device can be attached to a skin surface via an adhesive contact and a pressurization system provides a pressure to the contents of a fluid reservoir assembly. Improvements to dry powdered formulations for reconstitution for preferred use in the device are also disclosed.

Reconstituting infusion device

A medical fluid communication system is disclosed comprising a pump controller and a fluid detector. The fluid detector detects characteristics of the fluid and provides fluid measurements to the pump controller, which detects if the fluid is flowing in the medication delivery system. In the event fluid is not flowing due to an occlusion, the pump controller may attempt to resolve the occlusion or may provide a warning to a user that an occlusion is occurring.

System and method for detecting occlusions in a medication infusion system using pulsewise pressure signals

Growing community of inventors

Chapel Hills, NC, United States of America

Matthew S Ferriter